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Article
Detection of Immunoglobulin M and Immunoglobulin G Antibodies Against Orientia tsutsugamushi for Scrub Typhus Diagnosis and Serosurvey in Endemic Regions
To estimate the regional cutoff of optical density (OD) values for immunoglobulin M (IgM) antibodies against Orientia tsutsugamushi in serum and cerebrospinal fluid (CSF) for clinical diagnosis of scrub typhus an...
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Article
Open AccessDiversity of rotavirus genotypes circulating in children < 5 years of age hospitalized for acute gastroenteritis in India from 2005 to 2016: analysis of temporal and regional genotype variation
From 2016, the Government of India introduced the oral rotavirus vaccine into the national immunization schedule. Currently, two indigenously developed vaccines (ROTAVAC, Bharat Biotech; ROTASIIL, Serum Instit...
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Article
Open AccessRotavirus gastroenteritis in Indian children < 5 years hospitalized for diarrhoea, 2012 to 2016
In 2016, the Government of India introduced the oral rotavirus vaccine (ROTAVAC, Bharat Biotech, India) in 4 states of India as part of the Universal Immunization Programme, and expanded to 5 more states in 20...
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Article
Open AccessSafety monitoring of ROTAVAC vaccine and etiological investigation of intussusception in India: study protocol
ROTAVAC, an indigenous rotavirus vaccine, was introduced in the universal immunization program of India in four states in 2016 and expanded to five more states in 2017. The clinical trial on efficacy of ROTAVA...
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Article
Open AccessSeven years of the field epidemiology training programme (FETP) at Chennai, Tamil Nadu, India: an internal evaluation
During 2001–2007, the National Institute of Epidemiology (NIE), Chennai, Tamil Nadu, India admitted 80 trainees in its two-year Field Epidemiology Training Programme (FETP). We evaluated the first seven years ...
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Article
Prevalence, awareness, treatment, control and risk factors for hypertension in a rural population in South India
Hypertension is a major public health problem with prevalence ranging 22–30% in urban India. There are few data on hypertension epidemiology in rural India. We conducted a survey to estimate prevalence, awaren...
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Article
Open AccessA malaria outbreak in Naxalbari, Darjeeling district, West Bengal, India, 2005: weaknesses in disease control, important risk factors
An outbreak of malaria in Naxalbari, West Bengal, India, in 2005 was investigated to understand determinants and propose control measures. Malaria cases were slide-confirmed. Methods included calculation of an...
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Article
Cholera outbreak secondary to contaminated pipe water in an urban area, West Bengal, India, 2006
Outbreaks of cholera are common in West Bengal. In April 2006, Garulia municipality reported a cluster of diarrhea cases. We investigated this cluster to identify the etiological agent, source of transmission ...
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Article
Open AccessA Bayesian approach to study the space time variation of leprosy in an endemic area of Tamil Nadu, South India
In leprosy endemic areas, patients are usually spatially clustered and not randomly distributed. Classical statistical techniques fail to address the problem of spatial clustering in the regression model. Baye...
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Article
Open AccessMeasles transmission following the tsunami in a population with a high one-dose vaccination coverage, Tamil Nadu, India 2004–2005
On 26 December 2004, a tsunami struck the coast of the state of Tamil Nadu, India, where one-dose measles coverage exceeded 95%. On 29 December, supplemental measles immunization activities targeted children 6...