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On the role of H3.3 in retroviral silencing

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  1. Article

    Open Access

    Cohesin couples transcriptional bursting probabilities of inducible enhancers and promoters

    Innate immune responses rely on inducible gene expression programmes which, in contrast to steady-state transcription, are highly dependent on cohesin. Here we address transcriptional parameters underlying thi...

    Irene Robles-Rebollo, Sergi Cuartero, Adria Canellas-Socias… in Nature Communications (2022)

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  2. Article

    Open Access

    The order and logic of CD4 versus CD8 lineage choice and differentiation in mouse thymus

    CD4 and CD8 mark helper and cytotoxic T cell lineages, respectively, and serve as coreceptors for MHC-restricted TCR recognition. How coreceptor expression is matched with TCR specificity is central to underst...

    Mohammad M. Karimi, Ya Guo, **aokai Cui, Husayn A. Pallikonda… in Nature Communications (2021)

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  3. Article

    Open Access

    Surveillance of cohesin-supported chromosome structure controls meiotic progression

    Chromosome movements and programmed DNA double-strand breaks (DSBs) promote homologue pairing and initiate recombination at meiosis onset. Meiotic progression involves checkpoint-controlled termination of thes...

    Maikel Castellano-Pozo, Sarai Pacheco, Georgios Sioutas… in Nature Communications (2020)

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  4. Article

    Open Access

    LTR retrotransposons transcribed in oocytes drive species-specific and heritable changes in DNA methylation

    De novo DNA methylation (DNAme) during mouse oogenesis occurs within transcribed regions enriched for H3K36me3. As many oocyte transcripts originate in long terminal repeats (LTRs), which are heterogeneous eve...

    Julie Brind’Amour, Hisato Kobayashi, Julien Richard Albert… in Nature Communications (2018)

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