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Article
Open AccessNovel Alzheimer’s disease genes and epistasis identified using machine learning GWAS platform
Alzheimer’s disease (AD) is a complex genetic disease, and variants identified through genome-wide association studies (GWAS) explain only part of its heritability. Epistasis has been proposed as a major contr...
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Article
Open AccessA metabolic associated fatty liver disease risk variant in MBOAT7 regulates toll like receptor induced outcomes
The breakdown of toll-like receptor (TLR) tolerance results in tissue damage, and hyperactivation of the TLRs and subsequent inflammatory consequences have been implicated as risk factors for more severe forms...
