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    Open Access

    How autoreactive thymocytes differentiate into regulatory versus effector CD4+ T cells after avoiding clonal deletion

    Thymocytes bearing autoreactive T cell receptors (TCRs) are agonist-signaled by TCR/co-stimulatory molecules to either undergo clonal deletion or to differentiate into specialized regulatory T (Treg) or effector ...

    Xuguang Tai, Alyssa Indart, Mirelle Rojano, Jie Guo, Nicolai Apenes… in Nature Immunology (2023)

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