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Article
Open AccessGenome-wide identification of quantitative trait loci and candidate genes for seven carcass traits in a four-way intercross porcine population
Carcass traits are essential economic traits in the commercial pig industry. However, the genetic mechanism of carcass traits is still unclear. In this study, we performed a genome-wide association study (GWAS...
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Article
Study of loess ecological slope protection optimization measures and prediction of the erosion control effect
The large-scale management of ditches and implementation of land projects in loess areas have increased the arable land area but have caused considerable engineering issues, resulting in severe soil erosion. I...
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Article
Open AccessA novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens
The plasma membrane is enriched for receptors and signaling proteins that are accessible from the extracellular space for pharmacological intervention. Here we conducted a series of CRISPR screens using human ...
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Chapter and Conference Paper
Research on Electric Load Forecasting Considering Node Marginal Electricity Price Based on WNN
This research suggests an electric load forecasting method that takes into account the marginal price of electricity in order to further increase the forecasting accuracy for electric loads. By including the m...
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Article
Neural variability in three major psychiatric disorders
Across the major psychiatric disorders (MPDs), a shared disruption in brain physiology is suspected. Here we investigate the neural variability at rest, a well-established behavior-relevant marker of brain fun...
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Article
Open AccessAssociation of elevated levels of peripheral complement components with cortical thinning and impaired logical memory in drug-naïve patients with first-episode schizophrenia
Schizophrenia has been linked to polymorphism in genes encoding components of the complement system, and hyperactive complement activity has been linked to immune dysfunction in schizophrenia patients. Whether...
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Article
Open AccessHigh-resolution contrast-enhanced MRI with three-dimensional fast spin echo improved the diagnostic performance for identifying pituitary microadenomas in Cushing’s syndrome
To assess the diagnostic performance of high-resolution contrast-enhanced MRI (hrMRI) with three-dimensional (3D) fast spin echo (FSE) sequence by comparison with conventional contrast-enhanced MRI (cMRI) and ...
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Article
Open AccessTen-year outcomes after percutaneous coronary intervention versus coronary artery bypass grafting for multivessel or left main coronary artery disease: a systematic review and meta-analysis
Short-term and long-term comparative outcomes after percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) for multivessel coronary artery (MVCA) or left main coronary artery (LMCA...
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Article
Stem Cell-derived Extracellular Vesicles: A Promising Nano Delivery Platform to the Brain?
A very important cause of the frustration with drug therapy for central nervous system (CNS) diseases is the failure of drug delivery. The blood–brain barrier (BBB) prevents most therapeutic molecules from ent...
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Article
Serum uric acid is not associated with major depressive disorder in European and South American populations: a meta-analysis and two-sample bidirectional Mendelian Randomization study
Although previous epidemiological studies have demonstrated that serum uric acid (SUA) is associated with major depressive disorder (MDD), these analyses are prone to biases. Here, we applied the Mendelian Ran...
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Article
Open AccessLipidomics combined with transcriptomic and mass spectrometry imaging analysis of the Asiatic toad (Bufo gargarizans) during metamorphosis and bufadienolide accumulation
To adapt to life on land, Asiatic toads (Bufo gargarizans) must remodel their bodies and refine their chemical defenses in water. The full scope of the mechanisms underlying these processes has yet to be revealed...
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Article
Open AccessElectroconvulsive therapy combined with lithium developed reversible pure anomic aphasia: a case report
Electroconvulsive therapy (ECT) combined with mood stabilizers is an effective method of treatment for manic episodes; however, there are controversial views on its side effects.
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Article
Complementary value of metabolic and tau PET imaging in the diagnosis of corticobasal degeneration
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Article
Open AccessGenome-wide association study identifying genetic variants associated with carcass backfat thickness, lean percentage and fat percentage in a four-way crossbred pig population using SLAF-seq technology
Carcass backfat thickness (BFT), carcass lean percentage (CLP) and carcass fat percentage (CFP) are important to the commercial pig industry. Nevertheless, the genetic architecture of BFT, CLP and CFP is still...
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Article
Open AccessThe evaluation of IMERG and ERA5-Land daily precipitation over China with considering the influence of gauge data bias
Evaluating the accuracy of the satellite and reanalysis precipitation products is very important for understanding their uncertainties and potential applications. However, because of underestimation existing i...
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Article
Open AccessIdentification of key sex-specific pathways and genes in the subcutaneous adipose tissue from pigs using WGCNA method
Adipose tissues (ATs), including visceral ATs (VATs) and subcutaneous ATs (SATs), are crucial for maintaining energy and metabolic homeostasis. SATs have been found to be closely related to obesity and obesity...
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Article
Daytime passive radiative cooler using zeolite
As a passive, efficient, and renewable powerless cooling method, radiation cooling has received widespread attention in the field of energy conservation. Radiators with high reflectivity in the solar radiation...
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Article
3-Ketodihydrosphingosine reductase maintains ER homeostasis and unfolded protein response in leukemia
Sphingolipids and their metabolic pathways have been implicated in disease development and therapeutic response; however, the detailed mechanisms remain unclear. Using a sphingolipid network focused CRISPR/Cas...
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Article
Sustained effects of left-behind experience during childhood on mental health in Chinese university undergraduates
Rapid industrialization and urbanization in China have resulted in labor migrants leaving children behind. For left-behind children (LBC), disrupted parental attachment may increase the risk of psychiatric mor...
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Article
Open AccessTesting extra-linearity across a psychosis continuum
It is unclear whether psychotic experiences (PEs) gradually merge into states of clinical psychosis along a continuum which correspond to a dimensional classification or whether latent classes appear above a c...
