1,286 Result(s)
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The Microstructure and Properties of a Cryogenic Steel Fe-21Cr-6Ni-9Mn-N
An austenitic stainless steel 21-6-9, with improved cryogenic magnetic properties by manganese additions and strengthened mechanical properties by nitrogen additions, is currently being considered for critical...
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Determination of79Se with accelerator mass spectrometry technique
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cAMP-induced switching in turning direction of nerve growth cones
Development of the nervous system depends on the correct pathfinding and target recognition by the growing tip of an axon, the growth cone1,2,3. Diffusible or substrate-bound molecules present in the environment ...
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Erratum: cAMP-induced switching in turning direction of nerve growth cones
Nature 388, 275–279 (1997) The order of panels in Fig. 3 of this Letter is incorrect as published. Figure 3a–e should be labelled as f–j, and Fig. 3f–j should be labelled a–e.
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A new interpretation of the Himalayan orogenic belt
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Bioptical microcycles of laminated speleothems from China and their chronological significance
Interfaces of microlayers, in most stalagmites from China, consist of opaque and organic materials. Observed with microscope, the interfaces seem dark under transmitted light and luminiferous under reflected f...
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Neurotoxicity induces cleavage of p35 to p25 by calpain
Cyclin-dependent kinase 5 (cdk5) and its neuron-specific activator p35 are required for neurite outgrowth and cortical lamination1,2,3. Proteolytic cleavage of p35 produces p25, which accumulates in the brains of...
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Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1
Cleavage of amyloid precursor protein (APP) by the β- and γ-secretases generates the amino and carboxy termini, respectively, of the Aβ amyloidogenic peptides Aβ40 and Aβ42—the major constituents of the amyloi...
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Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
Phosphoinositide-3-OH kinases (PI(3)Ks) constitute a family of evolutionarily conserved lipid kinases that regulate a vast array of fundamental cellular responses, including proliferation, transformation, diff...
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The combined genotypes effect of ESR and FSHβ genes on litter size traits in five different pig breeds
Estrogen receptor (ESR) and Follicular-stimulating hormone beta subunit (FSHβ) genes were chosen as candidates to determine whether they control litter size and some other reproductive traits in swine. 269 sow...
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Depositional architecture and develo** settings of large-scale incised valley and submarine gravity flow systems in the Yinggehai and Qiongdongnan basins, South China Sea
In the Ying-Qiong basins in the South China Sea developed a set of giant inner shelf slope and submarine gravity flow deposits in the Ying-Huang formations since the Late Miocene. These deposits can be classif...
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Adaptation in the chemotactic guidance of nerve growth cones
Pathfinding by growing axons in the develo** nervous system may be guided by gradients of extracellular guidance factors. Analogous to the process of chemotaxis in microorganisms, we found that axonal growth...
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Cloning and identification of measles virus receptor gene from marmoset cells
The measles virus (MV) strains with mutated hemagglutinin gene (ha) lost the capacity to infect its sensitive host cells (Vero cells), but it may infect the marmoset B-lymphoblastoid cell line B95a. From above, w...
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Paleotemperature changes over the past 3000 years in eastern Bei**g, China: A reconstraction based on Mg/Sr records in a stalagmite
The Mg/Sr ratio in a stalagmite, which is directly proportional toD Mg/ca, the solid-liquid distribution coefficient of Mg, is proposed as a geochemical thermometer to estimate paleotemperature ch...
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Structural basis of the α1–β subunit interaction of voltage-gated Ca2+ channels
High-voltage-activated Ca2+ channels are essential for diverse biological processes. They are composed of four or five subunits, including α1, α2-δ, β and γ (ref. 1). Their expression and function are critically ...
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Recycling lower continental crust in the North China craton
Foundering of mafic lower continental crust into underlying convecting mantle has been proposed as one means to explain the unusually evolved chemical composition of Earth's continental crust1,2, yet direct evide...
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Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity
They may both look like small tubes but arteries and veins are in fact anatomically and functionally distinct. Little is known about how vein identity is established, but studies in mouse embryos now show that...
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Open AccessGenome sequencing in microfabricated high-density picolitre reactors
The proliferation of large-scale DNA-sequencing projects in recent years has driven a search for alternative methods to reduce time and cost. Here we describe a scalable, highly parallel sequencing system with...
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Correction: Corrigendum: Genome sequencing in microfabricated high-density picolitre reactors
Nature 437, 376–380 (2005)10.1038/nature03959 The following were omitted from the original author listing: Alex de Winter, James Drake, Robin Forte, Steve Hutchinson, William L. Lee, Michael Reifler and David ...
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Post-transcriptional gene silencing signal could move rapidly and bidirectionally in grafted Arabidopsis thaliana
RNA interference (RNAi), one of the newly found ways for post-transcriptional gene silencing, has been widely used to investigate gene functions through transgenic methods for introducing an RNA silencing sign...