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  1. Article

    Open Access

    Genetic diversity and prevalence of emerging Rickettsiales in Yunnan Province: a large-scale study

    Rickettsia and related diseases have been identified as significant global public health threats. This study involved comprehensive field and systematic investigations of various rickettsial organisms in Yunna...

    Chun-Hong Du, Rong **ang, Shuang-Shuang Bie, **ng Yang in Infectious Diseases of Poverty (2024)

  2. Article

    Open Access

    Modelling the rheology of living cell cytoplasm: poroviscoelasticity and fluid-to-solid transition

    Eukaryotic cell rheology has important consequences for vital processes such as adhesion, migration, and differentiation. Experiments indicate that cell cytoplasm can exhibit both elastic and viscous character...

    Namshad Thekkethil, Jakub Köry, Ming Guo in Biomechanics and Modeling in Mechanobiology (2024)

  3. Article

    Open Access

    UBQLN4 promotes the proliferation and invasion of non-small cell lung cancer cell by regulating PI3K/AKT pathway

    Ubiquilin-4 (UBQLN4), a member of the ubiquilin family, has received limited attention in cancer research to date. Here, we investigated for the first time the functional role and mechanism of UBQLN4 in non-sm...

    Li He, Heng Chen, Bin Ruan, Li He, Ming Luo in Journal of Cancer Research and Clinical On… (2024)

  4. No Access

    Article

    GSTO1 aggravates EGFR-TKIs resistance and tumor metastasis via deglutathionylation of NPM1 in lung adenocarcinoma

    Despite significantly improved clinical outcomes in EGFR-mutant lung adenocarcinoma, all patients develop acquired resistance and malignancy on the treatment of EGFR tyrosine kinase inhibitors (EGFR-TKIs). Und...

    Ning-xiang Shen, Ming-yu Luo, Wei-ming Gu, Miaomiao Gong, Hui-min Lei, Ling Bi in Oncogene (2024)

  5. No Access

    Article

    A multi-source heterogeneous medical data enhancement framework based on lakehouse

    Obtaining high-quality data sets from raw data is a key step before data exploration and analysis. Nowadays, in the medical domain, a large amount of data is in need of quality improvement before being used to...

    Ming Sheng, Shuliang Wang, Yong Zhang, Rui Hao in Health Information Science and Systems (2024)

  6. No Access

    Article

    Bispecific BCMA/CD19 targeted CAR-T cell therapy forces sustained disappearance of symptoms and anti-acetylcholine receptor antibodies in refractory myasthenia gravis: a case report

    Yong Zhang, Dan Liu, Zhouao Zhang, **aoyu Huang, Jiang Cao in Journal of Neurology (2024)

  7. Article

    Open Access

    Low friction under ultrahigh contact pressure enabled by self-assembled fluorinated azobenzene layers

    Extensive efforts have been made to pursue a low-friction state with promising applications in many fields, such as mechanical and biomedical engineering. Among which, the load capacity of the low-friction sta...

    Dandan Xue, Zhi Xu, Linyuan Guo, Wendi Luo, Liran Ma, Yu Tian, Ming Ma in Friction (2024)

  8. No Access

    Article

    A review of ultrafast laser micro/nano fabrication: Material processing, surface/interface controlling, and devices fabrication

    Ultrafast laser processing technology has offered a wide range of opportunities in micro/nano fabrication and other fields such as nanotechnology, biotechnology, energy science, and photonics due to its contro...

    Heng Guo, Jiawang **e, Guangzhi He, Dezhi Zhu, Ming Qiao, Jianfeng Yan in Nano Research (2024)

  9. No Access

    Article

    Resolvin D1 delivery to lesional macrophages using antioxidative black phosphorus nanosheets for atherosclerosis treatment

    The buildup of plaques in atherosclerosis leads to cardiovascular events, with chronic unresolved inflammation and overproduction of reactive oxygen species (ROS) being major drivers of plaque progression. Nan...

    Zhongshan He, Wei Chen, Kuan Hu, Yaoyao Luo, Wanqin Zeng, in Nature Nanotechnology (2024)

  10. No Access

    Article

    Stretchable continuous p-n alternating thermoelectric fibers for energy harvesting and sensing devices

    The increased human demand for an intelligent life puts forward a great requirement for lightweight, stretchable, and comfort sensing and energy harvesting devices. Stretchable thermoelectric fiber becomes ver...

    Mufang Li, Huijun Chen, Jiale Zhao, Ming **a in Advanced Composites and Hybrid Materials (2024)

  11. No Access

    Article

    Tool wear prediction based on a fusion model of data-driven and physical models in the milling process

    Precision tool wear prediction in the milling process is crucial in enhancing product quality and machining efficiency. Both data-driven models and physical models are vital for indirect tool wear prediction. ...

    Chang Fan, Zhao Zhang, Dinghua Zhang in The International Journal of Advanced Manu… (2024)

  12. Article

    Open Access

    Minimally invasive surgeries for spontaneous hypertensive intracerebral hemorrhage (MISICH): a multicenter randomized controlled trial

    Intracerebral hemorrhage (ICH) is a common stroke type with high morbidity and mortality. There are mainly three surgical methods for treating ICH. Unfortunately, thus far, no specific surgical method has been...

    **nghua Xu, Hua** Zhang, Jiashu Zhang, Ming Luo, Qun Wang, Yining Zhao in BMC Medicine (2024)

  13. Article

    Open Access

    Health economics study of paliperidone palmitate in the treatment of schizophrenia: a 12-month cohort study

    To analyze the economic benefits of paliperidone palmitate in the treatment of schizophrenia.

    **ng Luo, Fang Liu, ** Lu, Yuqi Cheng, **ufeng Xu, **aolin He in BMC Psychiatry (2024)

  14. Article

    Open Access

    Correction: Classical swine fever virus triggers RIG-I and MDA5-dependent signaling pathway to IRF-3 and NF-κB activation to promote secretion of interferon and inflammatory cytokines in porcine alveolar macrophages

    **ao-Ying Dong, Wen-Jun Liu, Ming-Qiu Zhao, Jia-Ying Wang in Virology Journal (2024)

  15. No Access

    Article

    Effects of different biogas slurry application patterns on nitrogen and phosphorus losses in a paddy field

    Biogas slurry, as a substitute for chemical fertilizers, is usually applied according to the needs of biogas slurry to be consumed at onetime. This poses a great risk of short-term nutrient overload in soils, ...

    Ming Li, Yinxiu Liu, Lin** Luo, Shanshan Ying in Paddy and Water Environment (2024)

  16. Article

    Open Access

    SRSF9 promotes cell proliferation and migration of glioblastoma through enhancing CDK1 expression

    Glioblastoma (GBM) is a highly aggressive and prevalent brain tumor that poses significant challenges in treatment. SRSF9, an RNA-binding protein, is essential for cellular processes and implicated in cancer p...

    Chunyuan Luo, Juan He, Yang Yang, Ke Wu in Journal of Cancer Research and Clinical On… (2024)

  17. Article

    Open Access

    Sex-specific associations of adolescent motherhood with cognitive function, behavioral problems, and autistic-like traits in offspring and the mediating roles of family conflict and altered brain structure

    Previous studies have linked adolescent motherhood to adverse neurodevelopmental outcomes in offspring, yet the sex-specific effect and underlying mechanisms remain unclear.

    Tai Ren, Lingli Zhang, Yongjie Liu, Qingli Zhang, Yunjun Sun, Wei Zhou in BMC Medicine (2024)

  18. No Access

    Article

    Evolutionary mechanism and frequency response of graphite electrode at extreme temperatures

    The battery management system is employed to monitor the external temperature of the lithium-ion battery in order to detect any potential overheating. However, this outside–in detection method often suffers fr...

    Shanpeng Pei, Zhiyong Zhang, **uli Zhang, Yan Liu, **ang Han, Linshan Luo in Nano Research (2024)

  19. No Access

    Article

    Anti-asthmatic Substances in the Chinese Herbal Formulation Huagai San Based on In Vitro and In Vivo Analysis and Network Pharmacology

    “Huagai san,” a Chinese classical herbal formulation, has been used for nearly 50 years to treat various conditions including bronchial asthma owing to its definite efficacy. It represents one of the few curre...

    Nan Zhou, Ran Wang, Lin-feng Liu, Wei Liu in Revista Brasileira de Farmacognosia (2024)

  20. Article

    Open Access

    Small extracellular vesicles from young plasma reverse age-related functional declines by improving mitochondrial energy metabolism

    Recent investigations into heterochronic parabiosis have unveiled robust rejuvenating effects of young blood on aged tissues. However, the specific rejuvenating mechanisms remain incompletely elucidated. Here ...

    **aorui Chen, Yang Luo, Qing Zhu, **gzi Zhang, Huan Huang, Yansheng Kan in Nature Aging (2024)

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