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The ASH1L-AS1-ASH1L axis controls NME1-mediated activation of the RAS signaling in gastric cancer

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  1. Article

    Open Access

    Effects of ultrasound-guided serratus plane block combined with general anesthesia on postoperative early quality of recovery and analgesia in patients undergoing transapical transcatheter aortic valve implantation surgery: study protocol for a randomized controlled trial

    Compared to traditional thoracotomy, transapical transcatheter aortic valve implantation (TAVI) surgery offers reduced trauma and faster recovery, fostering the adoption of enhanced recovery after surgery (ERA...

    Cheng **ao, Fang Chen, Lei Cao, Ming Yang, Yuting Tan, Guoyun Lin, Guiying Yang in Trials (2024)

  2. Article

    Open Access

    Gut microbiota-derived acetate attenuates lung injury induced by influenza infection via protecting airway tight junctions

    Gut microbiota (GM) have been implicated as important regulators of gastrointestinal symptom which is commonly occurred along with respiratory influenza A virus (IAV) infection, suggesting the involvement of t...

    Lei Hu, Li Sun, Chun Yang, Da-Wei Zhang, Yuan-Yuan Wei in Journal of Translational Medicine (2024)

  3. Article

    Open Access

    Correlating Reiff scores with clinical, functional, and prognostic factors: characterizing noncystic fibrosis bronchiectasis severity: validation from a nationwide multicenter study in Taiwan

    Our study aimed to confirm a simplified radiological scoring system, derived from a modified Reiff score, to evaluate its relationship with clinical symptoms and predictive outcomes in Taiwanese patients with ...

    Wen-Chien Cheng, Chia-Ling Chang, Chau-Chyun Sheu in European Journal of Medical Research (2024)

  4. Article

    Open Access

    Association between life’s essential 8 and frailty status among cancer survivors in the United States: a cross-sectional analysis

    Frailty not only affects disease survival but also impacts the long-term function and quality life of all adults diagnosed with and/or treated for cancer.The American Heart Association has introduced Life’s Es...

    **uxiu Qiu, Qidong Wu, Yiyi Zhang, Yingjie Zhu, Ming Yang, Li Tao in BMC Public Health (2024)

  5. Article

    Open Access

    Arginine-linked HPV-associated E7 displaying bacteria-derived outer membrane vesicles as a potent antigen-specific cancer vaccine

    Bacteria-based cancer therapy have demonstrated innovative strategies to combat tumors. Recent studies have focused on gram-negative bacterial outer membrane vesicles (OMVs) as a novel cancer immunotherapy str...

    Suyang Wang, Chao-Cheng Chen, Ming-Hung Hu in Journal of Translational Medicine (2024)

  6. Article

    Open Access

    The impact of caregiver burden on quality of life in family caregivers of patients with advanced cancer: a moderated mediation analysis of the role of psychological distress and family resilience

    The caregiver burden frequently experienced by family members tending to advanced cancer patients significantly impacts their psychological well-being and quality of life (QoL). Although family resilience migh...

    Panpan Cui, Ming Yang, Hengyu Hu, Chunyan Cheng, **nyi Chen in BMC Public Health (2024)

  7. Article

    Open Access

    FastEval Parkinsonism: an instant deep learning–assisted video-based online system for Parkinsonian motor symptom evaluation

    The Motor Disorder Society’s Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) is designed to assess bradykinesia, the cardinal symptoms of Parkinson’s disease (PD). However, it cannot capture the all-day v...

    Yu-Yuan Yang, Ming-Yang Ho, Chung-Hwei Tai, Ruey-Meei Wu in npj Digital Medicine (2024)

  8. Article

    Open Access

    Loss of LECT2 promotes ovarian cancer progression by inducing cancer invasiveness and facilitating an immunosuppressive environment

    Leukocyte cell-derived chemotaxin 2 (LECT2) is a multifunctional cytokine that can bind to several receptors and mediate distinct molecular pathways in various cell settings. Changing levels of LECT2 have been...

    Chin-Jui Wu, Ke-Fan Pan, Ji-Qing Chen, Yu -Chen Tao, Yu-Cheng Liu, Bo-Rong Chen in Oncogene (2024)

  9. Article

    Open Access

    Immune checkpoint inhibitors in cancer: the increased risk of atherosclerotic cardiovascular disease events and progression of coronary artery calcium

    Immune checkpoint inhibitors (ICIs) have contributed to a significant advancement in the treatment of cancer, leading to improved clinical outcomes in many individuals with advanced disease. Both preclinical a...

    Bingxin Gong, Yusheng Guo, Yi Li, **g Wang, Guofeng Zhou, Yong-hao Chen in BMC Medicine (2024)

  10. Article

    Open Access

    A novel computer-assisted tool for 3D imaging of programmed death-ligand 1 expression in immunofluorescence-stained and optically cleared breast cancer specimens

    Programmed death-1 (PD-1) and programmed death-ligand 1 (PD-L1) are the two most common immune checkpoints targeted in triple-negative breast cancer (BC). Refining patient selection for immunotherapy is non-tr...

    Yi-Hsuan Lee, Chung-Yen Huang, Yu-Han Hsieh, Chia-Hung Yang, Yu-Ling Hung in BMC Cancer (2024)

  11. Article

    Open Access

    Revealing the mechanism of 755-nm long-pulsed alexandrite laser in inhibiting infantile hemangioma endothelial cells through transcriptome sequencing

    Laser therapy has shown promising outcomes in treating infantile hemangiomas. However, the molecular mechanisms underlying laser treatment for IH remain incompletely elucidated. This study aimed to unravel th...

    Chen Ke, Changhan Chen, Ming Yang, Hao Chen, Liqun Li in Lasers in Medical Science (2024)

  12. Article

    Open Access

    CVD phenoty** in oncologic disorders: cardio-miRNAs as a potential target to improve individual outcomes in revers cardio-oncology

    With the increase of aging population and prevalence of obesity, the incidence of cardiovascular disease (CVD) and cancer has also presented an increasing tendency. These two different diseases, which share so...

    Ming Yang, Tiepeng Li, Shu** Guo, Kang** Song in Journal of Translational Medicine (2024)

  13. Article

    Open Access

    Ultrasound-guided erector spinae plane block for perioperative analgesia in patients undergoing laparoscopic nephrectomies surgery: a randomized controlled trial

    Laparoscopic nephrectomy is a commonly utilized surgical approach for the management of renal cancer. Despite its widespread acceptance, postoperative pain management remains a significant challenge for many p...

    Ming Yang, Lei Cao, Tong Lu, Cheng **ao, Zhuoxi Wu, Xuetao Jiang, Wei Wang in Trials (2024)

  14. Article

    Open Access

    Cholesterol-modified prognostic nutritional index (CPNI) as an effective tool for assessing the nutrition status and predicting survival in patients with breast cancer

    Malnutrition is associated with poor overall survival (OS) in breast cancer patients; however, the most predictive nutritional indicators for the prognosis of patients with breast cancer are not well-establish...

    **yu Shi, Tong Liu, Yizhong Ge, Chenan Liu, Qi Zhang, Hailun **e in BMC Medicine (2023)

  15. Article

    Open Access

    A real-world case–control study on the efficacy and safety of pulsed field ablation for atrial fibrillation

    The primary objective of this study was to evaluate the efficacy and safety of pulsed field ablation in individuals diagnosed with atrial fibrillation.

    Ming Yang, Peng-yu Wang, Ying-lu Hao, Mei Liang in European Journal of Medical Research (2023)

  16. Article

    Open Access

    Accurate interpretation of p53 immunohistochemical patterns is a surrogate biomarker for TP53 alterations in large B-cell lymphoma

    To clarify the relationship between p53 immunohistochemistry (IHC) staining and TP53 alterations (including mutations and deletions) in large B-cell lymphomas (LBCLs) and to explore the possibility of p53 IHC exp...

    **nyi Li, Danju Luo, Liling Zhang, Qiuhui Li, Jun Fan, Jiwei Zhang, Bo Huang in BMC Cancer (2023)

  17. Article

    Open Access

    Correction: Non-enzymatic heparanase enhances gastric tumor proliferation via TFEB-dependent autophagy

    Min Yang, Bo Tang, Sumin Wang, Li Tang, Dalin Wen, Israel Vlodavsky in Oncogenesis (2023)

  18. Article

    Open Access

    International guideline on natural orifice specimen extraction surgery (NOSES) for colorectal cancer (2023 version)

    In recent years, natural orifice specimen extraction surgery (NOSES) has gained widespread attention as an alternative approach. Although the safety and feasibility of NOSES have been well documented, many que...

    Zheng Liu, Xu Guan, Mingguang Zhang, **yue Hu, Ming Yang in Holistic Integrative Oncology (2023)

  19. Article

    Open Access

    Knowledge, attitude, and practice of nephrologists on the decision for renal replacement therapy

    This study aimed to investigate the Knowledge, Attitude, and Practice (KAP) of nephrologists on the decision of renal replacement therapy (RRT), including peritoneal dialysis, hemodialysis, and kidney transpla...

    **aofang Hu, Ming Yang, **angyi Li, Yu Chen, Shaxi Ouyang, Lin Li in BMC Public Health (2023)

  20. Article

    Open Access

    Characterization of mesenchymal stem cells in human fetal bone marrow by single-cell transcriptomic and functional analysis

    Bone marrow mesenchymal stromal/stem cells (MSCs) are a heterogeneous population that can self-renew and generate stroma, cartilage, fat, and bone. Although a significant progress has been made toward recogniz...

    ** Zhang, Ji Dong, **aoying Fan, Jun Yong in Signal Transduction and Targeted Therapy (2023)

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