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    Somatic and germline mutations in the tumor suppressor gene PARK2 impair PINK1/Parkin-mediated mitophagy in lung cancer cells

    PARK2, which encodes Parkin, is a disease-causing gene for both neurodegenerative disorders and cancer. Parkin can function as a neuroprotector that plays a crucial role in the regulation of mitophagy, and germli...

    Zeng-li Zhang, Na-na Wang, Qi-lian Ma, Yang Chen, Li Yao… in Acta Pharmacologica Sinica (2020)