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Open AccessAuthor Correction: Neuroprotective effects of ATPase inhibitory factor 1 preventing mitochondrial dysfunction in Parkinson's disease
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Open AccessNeuroprotective effects of ATPase inhibitory factor 1 preventing mitochondrial dysfunction in Parkinson's disease
Mitochondrial dysfunction is a key element in the progression of Parkinson’s disease (PD). The inefficient operation of the electron transport chain (ETC) impairs energy production and enhances the generation ...
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Open AccessSleep duration and mortality in Korean adults: a population-based prospective cohort study
Increasing evidence suggests that sleep duration is associated with risks of various diseases including type 2 diabetes, cardiovascular disease (CVD), and certain types of cancer. However, the relationship wit...
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Open AccessLifestyle risk score and mortality in Korean adults: a population-based cohort study
Individual lifestyle risk factors have been associated with an increased risk of mortality. However, limited evidence is available on the combined association of lifestyle risk factors with mortality in non-We...
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Open AccessThe association between genetic variants of angiopoietin-like 3 and risk of diabetes mellitus is modified by dietary factors in Koreans
The role of angiopoietin-like 3 (ANGPTL3) in blood lipid levels, cardiovascular disease risk, and glucose metabolism has received wide attention. This study aimed to examine whether rs11207997 in ANGPTL3 is assoc...
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Open AccessSerum metabolite profile associated with incident type 2 diabetes in Koreans: findings from the Korean Genome and Epidemiology Study
The identification of metabolic alterations in type 2 diabetes (T2D) is useful for elucidating the pathophysiology of the disease and in classifying high-risk individuals. In this study, we prospectively exami...
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Open AccessLongitudinal association between egg consumption and the risk of cardiovascular disease: interaction with type 2 diabetes mellitus
It remains unclear if high egg consumption has beneficial or adverse effects on cardiometabolic health. The present study prospectively evaluated the longitudinal association between egg-consumption levels and...
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Open AccessExploring the utility of alcohol flushing as an instrumental variable for alcohol intake in Koreans
Previous studies have indicated an association of higher alcohol intake with cardiovascular disease and related traits, but causation has not been definitively established. In this study, the causal effect of ...
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Open AccessMyocardial metabolic alterations in mice with diet-induced atherosclerosis: linking sulfur amino acid and lipid metabolism
Atherosclerosis is a leading cause of cardiovascular disease (CVD), but the effect of diet on the atherosclerotic heart’s metabolism is unclear. We used an integrated metabolomics and lipidomics approach to ev...
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Open AccessCorrection: Corrigendum: Alcohol intake and cardiovascular risk factors: A Mendelian randomisation study
Scientific Reports 5: Article number: 18422; published online: 21 December 2015; updated: 27 May 2016 This Article contains typographical errors in Table 6. In the column ‘OR (95% CI) by IV estimation’, the Ca...
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Open AccessAlcohol intake and cardiovascular risk factors: A Mendelian randomisation study
Mendelian randomisation studies from Asia suggest detrimental influences of alcohol on cardiovascular risk factors, but such associations are observed mainly in men. The absence of associations of genetic vari...
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Open AccessCathepsin L derived from skeletal muscle cells transfected with bFGF promotes endothelial cell migration
Gene transfer of basic fibroblast growth factor (bFGF) has been shown to induce significant endothelial migration and angiogenesis in ischemic disease models. Here, we investigate what factors are secreted fro...