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Article
Comparison of multivariate calibration models for glucose, urea, and lactate from near-infrared and Raman spectra
Partial least-squares (PLS) calibration models have been generated from a series of near-infrared (near-IR) and Raman spectra acquired separately from sixty different mixed solutions of glucose, lactate, and u...
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Article
QPEEG analysis of the effects of sodium valproate on adult Chinese patients with generalized tonic-clonic seizures
Objectives EEG effects of the sustained-release form of sodium valproate (SR-VPA) are unknown, although it is widely used in Chinese patients with generalized tonicclonic seizures (GTCS). Methods Fourteen newl...
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Article
Calycosin-7-O-β-d-glucoside attenuates myocardial ischemia–reperfusion injury by activating JAK2/STAT3 signaling pathway via the regulation of IL-10 secretion in mice
Calycosin-7-O-β-d-glucoside (CG) is the component of Astragali Radix, and the aim of the present study is to investigate whether CG protects myocardium from I/R-induced damage by the regulation of IL-10/JAK2/STAT...
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Article
Open AccessAKT1-CREB stimulation of PDGFRα expression is pivotal for PTEN deficient tumor development
As evidenced by the behavior of loss-of-function mutants of PTEN in the context of a gain-of-function mutation of AKT1, the PTEN-AKT1 signaling pathway plays a critical role in human cancers. In this study, we...
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Article
Halomonas **caotanensis sp. nov., isolated from the Pamir Plateau degrading polycyclic aromatic hydrocarbon
A Gram-strain-negative, rod-shaped, aerobic bacterium, designated strain TRM 85114T, was isolated from the **caotan wetland in the Pamir Plateau of China. This strain grew optimally at 30 °C and pH 6.0 in the pr...
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Article
Open AccessDecoding the metastatic potential and optimal postoperative adjuvant therapy of melanoma based on metastasis score
Metastasis is a formidable challenge in the prognosis of melanoma. Accurately predicting the metastatic potential of non-metastatic melanoma (NMM) and determining effective postoperative adjuvant treatments fo...
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Article
A Novel Pancreatic Cancer Hypoxia Status Related Gene Signature for Prognosis and Therapeutic Responses
Pancreatic cancer (PAC) is a highly fatal and aggressive type of cancer. Hypoxia is a common feature of PAC. The aim of this study was to develop a hypoxia status-related prognostic model for predicting the su...