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Acute terminal pancreatitis occurring in jejunal heterotopic pancreas
Conclusion. We report a unique case of acute terminal pancreatitis occurring in the jejunal heterotopic pancreas. Unlike previously reported cases, acute pancreatitis was not found histologically in the ordina...
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Article
Nonfunctioning endocrine tumor of the pancreas with extrapancreatic growth and cyst formation: Report of a case
We report a case of nonfunctioning endocrine tumor of the pancreas with extrapancreatic growth and cyst formation. A 48-year-old woman was admitted to our hospital with an upper abdominal mass, which was detec...
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Article
A case of spindle cell carcinoma of the breast-long survival achieved by multiple surgical treatment
Spindle cell carcinoma of the breast was formerly called carcinosarcoma, and is relatively rare. We report a case of spindle cell carcinoma of the breast. The patient was treated with multiple surgeries and ac...
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Article
A Cyst of Benign Mediastinal Teratoma Demonstrating a Peculiar Development: Report of a Case
A 28-year-old woman developed repeated neck swelling and remission over a 4-month period. Benign mediastinal teratomas also extended along her cervical region. It was not a teratoma which primarily developed ...
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Article
Sclerosing perineurioma: a clinicopathological study of five cases and diagnostic utility of immunohistochemical staining for GLUT1
We reviewed five cases of sclerosing perineurial tumor of the hand. Four patients were male and one was female with ages ranging from 11 years to 49 years (mean 26 years). The predominant reason for consultati...
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Article
Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models
Aurora-A, a serine/threonine mitotic kinase, was reported to be overexpressed in various human cancers, and its overexpression induces aneuploidy, centrosome amplification and tumorigenic transformation in cul...
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Article
Classification of types of intraductal papillary-mucinous neoplasm of the pancreas: a consensus study
Now that more than two decades have passed since the first reports of intraductal papillary-mucinous neoplasms (IPMNs), it has become clear that IPMN consists of a spectrum of neoplasms with both morphological...
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Article
Intraductal papillary mucinous neoplasm (IPMN) of the gastric-type with focal nodular growth of the arborizing papillae: a case of high-grade transformation of the gastric-type IPMN
We present a case of intraductal papillary mucinous neoplasm (IPMN) of the pancreas, demonstrating a process of high-grade transformation of the gastric-type IPMN. An 83-year-old Japanese woman underwent pylor...
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Article
Gene expression of ferredoxin reductase predicts outcome in patients with metastatic colorectal cancer treated by 5-fluorouracil plus leucovorin
Purpose: Ferredoxin reductase (FDXR) is a putative contributor to p53-mediated apoptosis from 5-fluorouracil (5-FU) through the generation of oxidative stress in the mitochondria. However...
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Article
Ciliary ultrastructure in two sisters with Kartagener's syndrome
Kartagener's syndrome (KS) is a clinical variant of primary ciliary dyskinesia involving situs inversus associated with chronic airway infections. We studied two sisters; the elder one had dextrocardia and sco...
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Multicentric invasive carcinomas derived from intraductal papillary mucinous neoplasm (IPMN) of the pancreas: report of a case
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Article
Squamous intraepithelial neoplasia of the esophagus: past, present, and future
With regard to the esophagus, the term “squamous dysplasia” has been used in European countries, the United States, and China, while its use is controversial in Japan. Recently, “low-grade intraepithelial neop...
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Article
Extranodular background liver parenchyma of focal nodular hyperplasia: histopathological characteristics
Focal nodular hyperplasia (FNH) of the liver is considered to develop as a hyperplastic response to a preexisting vascular abnormality. From the pathogenic point of view, we studied histological alterations in...
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Article
Association of hypoxia-inducible factor-1 expression with histology in epithelial ovarian tumors: a quantitative analysis of HIF-1
Hypoxia-inducible factor-1 (HIF-1) is an essential transcription factor that mediates cellular and systemic homeostatic responses to reduced oxygen availability in mammals. So far, using immunohistochemistry w...
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Article
Pathology of non-Helicobacter pylori gastritis: extending the histopathologic horizons
The development of modern endoscopic techniques, easier and greater access to healthcare, and interest in Helicobacter pylori infection and its implications have all led to a significant increase in upper endosco...
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Article
Open AccessPeritoneal keratin granuloma associated with endometrioid adenocarcinoma of the uterine corpus
We present a 69-year-old woman with a chief complaint of postmenopausal bleeding. She was diagnosed as having an endometrioid adenocarcinoma by biopsy, and underwent a total abdominal hysterectomy. At the time...
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Article
Biopsy interpretation of colonic biopsies when inflammatory bowel disease is excluded
The interpretation of colonic biopsies related to inflammatory conditions can be challenging because the colorectal mucosa has a limited repertoire of morphologic responses to various injurious agents. Only fe...
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Erratum to: Classification of types of intraductal papillary-mucinous neoplasm of the pancreas: a consensus study
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Open AccessMesonephric adenocarcinoma with a sarcomatous component, a notable subtype of cervical carcinosarcoma: a case report and review of the literature
Carcinosarcoma of the uterine cervix is less common than its counterpart in the uterine corpus. On the other hand, mesonephric adenocarcinoma is also a rare neoplasm in the uterine cervix, and it has been repo...
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Giant pedunculated pilomatrix carcinoma on the upper limb: A rare clinical appearance