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  1. No Access

    Protocol

    Bacterial Expression and Purification of C1 and C2 Domains of Protein Kinase C Isoforms

    Protein kinase C (PKC) contains two types of membrane-targeting domains, C1 and C2 domains, in its regulatory region (1–5). It has been shown that C1 and C2 domains of conventional PKCs (α, βI, βII, and γ) and C1...

    Wonhwa Cho, Michelle Digman, Bharath Ananthanarayanan… in Protein Kinase C Protocols (2003)

  2. No Access

    Article

    One photon up, one photon down

    A microscopy technique based on stimulated Raman scattering achieves label-free imaging with very high sensitivity.

    Enrico Gratton, Michelle Digman in Nature Biotechnology (2009)

  3. Article

    Open Access

    Abstracts from the 3rd Conference on Aneuploidy and Cancer: Clinical and Experimental Aspects

    Athel Cornish-Bowden, Athel Cornish-Bowden, David Rasnick… in Molecular Cytogenetics (2017)

    Download PDF (449 KB) View Article

  4. No Access

    Chapter and Conference Paper

    Changes in Membrane Fluidity of the Expanded Mutant Huntingtin Protein with the Phasor-FLIM Approach Signatures of Laurdan

    Huntington’s Disease, known for the presence of extended polyQ repeats in the huntingtin protein, has pathological effects on cellular membrane organelles. Here, we describe disturbances in membrane organizati...

    Balam Benítez-Mata, Francesco Palomba… in XLV Mexican Conference on Biomedical Engin… (2023)