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  1. Article

    Open Access

    Bone sarcoma patient-derived xenografts are faithful and stable preclinical models for molecular and therapeutic investigations

    Standard therapy of osteosarcoma (OS) and Ewing sarcoma (EW) rests on cytotoxic regimes, which are largely unsuccessful in advanced patients. Preclinical models are needed to break this impasse. A panel of pat...

    Patrizia Nanni, Lorena Landuzzi, Maria Cristina Manara, Alberto Righi in Scientific Reports (2019)