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  1. Article

    Open Access

    Multi-omic profiling reveals discrepant immunogenic properties and a unique tumor microenvironment among melanoma brain metastases

    Melanoma brain metastases (MBM) are clinically challenging to treat and exhibit variable responses to immune checkpoint therapies. Prior research suggests that MBM exhibit poor tumor immune responses and are e...

    Gino K. In, Jennifer R. Ribeiro, Jun Yin, Joanne **u in npj Precision Oncology (2023)

  2. Article

    The development of anti-interleukin-2 antibodies in patients treated with recombinant human interleukin-2 (IL-2)

    Approximately 65% (11/17) of cancer patients participating in an ongoing Phase I clinical trial with recombinant interleukin-2 developed nonneutralizing serum IgG anti-interleukin-2 antibodies within 1 month o...

    Mark Allegretta, Michael B. Atkins, Roy A. Dempsey in Journal of Clinical Immunology (1986)