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  1. Article

    Open Access

    Multi-omic profiling reveals discrepant immunogenic properties and a unique tumor microenvironment among melanoma brain metastases

    Melanoma brain metastases (MBM) are clinically challenging to treat and exhibit variable responses to immune checkpoint therapies. Prior research suggests that MBM exhibit poor tumor immune responses and are e...

    Gino K. In, Jennifer R. Ribeiro, Jun Yin, Joanne **u… in npj Precision Oncology (2023)

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    Reference Work Entry In depth

    Tregs

    Regulatory T cells (Tregs) are a subtype of T cells with immune suppressive function and play a key role in immune self-tolerance. Its immune inhibitory function has been implicated as the important mechanism ...

    Jong Chul Park, Michael. B. Atkins in Cancer Therapeutic Targets (2017)

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    Living Reference Work Entry In depth

    Tregs

    Regulatory T cells (Tregs) are a subtype of T cells with immune suppressive function and play a key role in immune self-tolerance. Its immune inhibitory function has been implicated as the important mechanism ...

    Jong Chul Park, Michael B. Atkins in Cancer Therapeutic Targets