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within Michael J. Chao Remove this filter Human Genetics Remove this filter

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  1. Article

    Open Access

    Methylation of class II transactivator gene promoter IV is not associated with susceptibility to Multiple Sclerosis

    Multiple sclerosis (MS) is a complex trait in which alleles at or near the class II loci HLA-DRB1 and HLA-DQB1 contribute significantly to genetic risk. The MHC class II transactivator (MHC2TA) is the master cont...

    Sreeram V Ramagopalan, David A Dyment, Katie M Morrison… in BMC Medical Genetics (2008)

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    Article

    Parental transmission of HLA-DRB1*15 in multiple sclerosis

    Multiple sclerosis (MS) is a complex trait in which HLA-DRB1*15 bearing MHC haplotypes increase risk of MS in people of Northern European descent. In this investigation of 7,334 individuals from 1,515 MS families...

    Sreeram V. Ramagopalan, Blanca M. Herrera, Jordana T. Bell… in Human Genetics (2008)