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  1. Article

    Open Access

    TERT Copy Number Alterations, Promoter Mutations and Rearrangements in Adrenocortical Carcinomas

    Molecular characterization of adrenocortical carcinomas (ACC) by The Cancer Genome Atlas (TCGA) has highlighted a high prevalence of TERT alterations, which are associated with disease progression. Herein, 78 ACC...

    Sounak Gupta, Helen Won, Kalyani Chadalavada, Gouri J. Nanjangud… in Endocrine Pathology (2022)

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  2. Article

    Phase II study of trastuzumab with modified docetaxel, cisplatin, and 5 fluorouracil in metastatic HER2-positive gastric cancer

    Trastuzumab with cisplatin and fluoropyrimidine is the standard treatment in metastatic HER2-positive gastric or gastroesophageal (GE) junction adenocarcinoma; however, there is limited data on the efficacy of...

    Sebastian Mondaca, Matthew Margolis, Francisco Sanchez-Vega… in Gastric Cancer (2019)

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  3. No Access

    Article

    The emerging clinical relevance of genomics in cancer medicine

    The combination of next-generation sequencing and advanced computational data analysis approaches has revolutionized our understanding of the genomic underpinnings of cancer development and progression. The co...

    Michael F. Berger, Elaine R. Mardis in Nature Reviews Clinical Oncology (2018)