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  1. No Access

    Article

    Solid-phase peptide synthesis: from standard procedures to the synthesis of difficult sequences

    This protocol for solid-phase peptide synthesis (SPPS) is based on the widely used Fmoc/tBu strategy, activation of the carboxyl groups by aminium-derived coupling reagents and use of PEG-modified polystyrene ...

    Irene Coin, Michael Beyermann, Michael Bienert in Nature Protocols (2007)

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    Chapter and Conference Paper

    N,O-Acyl Shifts: Unexpected Side-Reaction and Beneficial Tool in Fmoc-Chemistry

    Louis A. Carpino, Calin D. Sferdean, Irene Coin in Understanding Biology Using Peptides (2006)

  3. No Access

    Chapter

    Protected amino acid chlorides: Coupling reagents suitable for the most highly hindered systems

    Michael Beyermann, Dumitru Ionescu, Petra Henklein in Peptides Frontiers of Peptide Science (2002)

  4. No Access

    Chapter

    Efficient assembly of stable site-directed fluorescence labeled peptides

    Holger Wenschuh, Ulrich Schaible, Stephanie Lamer in Peptides Frontiers of Peptide Science (2002)

  5. No Access

    Article

    Influence of proline and β-turn mimetics on the cyclization of penta- and hexapeptides

    Proline and Pro-derived peptidomimetics, such as meoxPro-Oic (4-methoxy-proline-octahydro indolic acid), and DBF (2-aminoethyl-6-dibenzofuran propionic acid) were introduced into thymopentin-derived penta- [SP...

    Jana Klose, Angelika Ehrlich, Michael Bienert in Letters in Peptide Science (1998)

  6. No Access

    Article

    Influence of proline and β-turn mimetics on the cyclization of penta- and hexapeptides

    Proline and Pro-derived peptidomimetics, such as meoxPro-Oic (4-methoxy-proline-octahydro indolic acid), and DBF (2-aminoethyl-6-dibenzofuran propionic acid) were introduced into thymopentin-derived penta-[SP5...

    Jana Klose, Angelika Ehrlich, Michael Bienert in Letters in Peptide Science (1998)

  7. No Access

    Article

    Synthesis of Fmoc-amino acid fluorides via DAST, an alternative fluorinating agent

    DAST [(diethylamino)sulfur trifluoride] has shown to be an excellent alternative fluorinating agent for synthesis of Fmoc-amino acid fluorides. The use of DAST is advantageous relative to other fluorinating ag...

    Christine Kaduk, Holger Wenschuh, Michael Beyermann in Letters in Peptide Science (1996)

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    Chapter

    Tritium Labeling of Brain Peptides

    During the past decade, radiolabeling of biologically active peptides has become a widely applied and essential technique for a variety of biochemical and physiological investigations.

    István Teplán, Imre Mező, Károly Nikolics in Hormonally Active Brain Peptides (1982)