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  1. Article

    Open Access

    Single-molecule studies of high-mobility group B architectural DNA bending proteins

    Protein–DNA interactions can be characterized and quantified using single molecule methods such as optical tweezers, magnetic tweezers, atomic force microscopy, and fluorescence imaging. In this review, we dis...

    Divakaran Murugesapillai, Micah J. McCauley, L. James Maher III… in Biophysical Reviews (2017)

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    Article

    Oligomerization transforms human APOBEC3G from an efficient enzyme to a slowly dissociating nucleic acid-binding protein

    The human APOBEC3 proteins are a family of DNA-editing enzymes that play an important role in the innate immune response against retroviruses and retrotransposons. APOBEC3G is a member of this family that inhi...

    Kathy R. Chaurasiya, Micah J. McCauley, Wei Wang, Dominic F. Qualley… in Nature Chemistry (2014)

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    Article

    Untying a nanoscale knot

    Mechanical unfolding of a single DNA G-quadruplex structure with and without a stabilizing ligand can be used to calculate the binding strength of the ligand and could help to identify drugs to target these im...

    Micah J. McCauley, Mark C. Williams in Nature Chemistry (2011)