654 Result(s)
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Miaomiao **n
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Article
Open AccessBNIP3-mediated mitophagy boosts the competitive growth of Lenvatinib-resistant cells via energy metabolism reprogramming in HCC
An increasing evidence supports that cell competition, a vital selection and quality control mechanism in multicellular organisms, is involved in tumorigenesis and development; however, the mechanistic contrib...
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Open AccessStable peptide-assembled nanozyme mimicking dual antifungal actions
Natural antimicrobial peptides (AMPs) and enzymes (AMEs) are promising non-antibiotic candidates against antimicrobial resistance but suffer from low efficiency and poor stability. Here, we develop peptide nan...
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Open AccessClinical serum lipidomic profiling revealed potential lipid biomarkers for early diabetic retinopathy
Diabetic retinopathy (DR) is a serious complication of diabetes featuring abnormal lipid metabolism. However, the specific lipid molecules associated with onset and progression remain unclear. We used a broad-...
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Open AccessFacet-selective growth of halide perovskite/2D semiconductor van der Waals heterostructures for improved optical gain and lasing
The tunable properties of halide perovskite/two dimensional (2D) semiconductor mixed-dimensional van der Waals heterostructures offer high flexibility for innovating optoelectronic and photonic devices. Howeve...
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Open AccessMultiomic analysis of monocyte-derived alveolar macrophages in idiopathic pulmonary fibrosis
Monocyte-derived alveolar macrophages (Mo_AMs) are increasingly recognised as potential pathogenic factors for idiopathic pulmonary fibrosis (IPF). While scRNAseq analysis has proven valuable in the transcript...
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Open AccessData-driven approaches linking wastewater and source estimation hazardous waste for environmental management
Industrial enterprises are major sources of contaminants, making their regulation vital for sustainable development. Tracking contaminant generation at the firm-level is challenging due to enterprise heterogen...
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Open AccessPeak detection in intracranial pressure signal waveforms: a comparative study
The monitoring and analysis of quasi-periodic biological signals such as electrocardiography (ECG), intracranial pressure (ICP), and cerebral blood flow velocity (CBFV) waveforms plays an important role in the...
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Open AccessCFNAM-PG: Bridging Phonetic and Glyphic Information for Chinese Full Name and Abbreviation Matching Based on Simbert and DenseNet
Matching abbreviated names with their full names (full-abbr matching) plays a key role in data integration, address matching, information retrieval, and other fields. Traditional full-abbr matching technology ...
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Open AccessVHL suppresses UBE3B-mediated breast tumor growth and metastasis
Protein homeostasis is predominantly governed through post-translational modification (PTM). UBE3B, identified as an oncoprotein, exhibits elevated protein levels in breast cancer. However, the impact of PTM o...
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Open AccessVariational AdaBoost knowledge distillation for skin lesion classification in dermatology images
Knowledge Distillation has shown promising results for classifying skin lesions in dermatology images. Traditional knowledge distillation typically involves the student model passively mimicking the teacher mo...
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Open AccessEffect of tissue tension on magnetic compression anastomosis of digestive tract
With the increasing application of magnetic compression anastomosis (MCA) in gastrointestinal anastomosis, we identified an interesting phenomenon that an anastomosis is more prone to stenosis after endoscopic...
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Open AccessLAPTM4B counteracts ferroptosis via suppressing the ubiquitin-proteasome degradation of SLC7A11 in non-small cell lung cancer
Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related deaths worldwide, necessitating the identification of novel therapeutic targets. Lysosome Associated Protein Transmembrane 4B (LAPTM4B) i...
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Open AccessThe deubiquitinating protein OTUD6B promotes lung adenocarcinoma progression by stabilizing RIPK1
There is growing evidence indicating that deubiquitinating enzymes may contribute to tumor progression and can serve as promising therapeutic targets.
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Open AccessAerobic exercise-induced HIF-1α upregulation in heart failure: exploring potential impacts on MCT1 and MPC1 regulation
The terminal stage of ischemic heart disease develops into heart failure (HF), which is characterized by hypoxia and metabolic disturbances in cardiomyocytes. The hypoxic failing heart triggers hypoxia-inducib...
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Open AccessTEX19 increases the levels of CDK4 and promotes breast cancer by disrupting SKP2-mediated CDK4 ubiquitination
Globally, breast cancer in women is the fifth leading cause of cancer death. There is an urgent need to explore the molecular mechanism of breast cancer proliferation and metastasis.
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Open AccessGlucose deprivation triggers DCAF1-mediated inactivation of Rheb-mTORC1 and promotes cancer cell survival
Low glucose is a common microenvironment for rapidly growing solid tumors, which has developed multiple approaches to survive under glucose deprivation. However, the specific regulatory mechanism remains large...
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Open AccessPrediction models for amputation after diabetic foot: systematic review and critical appraisal
Numerous studies have developed or validated prediction models aimed at estimating the likelihood of amputation in diabetic foot (DF) patients. However, the quality and applicability of these models in clinica...
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Open AccessThe relationship between family functioning and social media addiction among university students: a moderated mediation model of depressive symptoms and peer support
Social media addiction (SMA) is an increasing problem, especially among young adults. Little is known about university students’ SMA and family functioning. This study aimed to explore the mediating effect of ...
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Open AccessLightweight strip steel defect detection algorithm based on improved YOLOv7
The precise identification of surface imperfections in steel strips is crucial for ensuring steel product quality. To address the challenges posed by the substantial model size and computational complexity in ...
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Open AccessTime-course swRNA-seq uncovers a hierarchical gene regulatory network in controlling the response-repair-remodeling after wounding
Wounding initiates intricate responses crucial for tissue repair and regeneration. Yet, the gene regulatory networks governing wound healing remain poorly understood. Here, employing single-worm RNA sequencing...
