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Open AccessPrediction of TKI response in EGFR-mutant lung cancer patients-derived organoids using malignant pleural effusion
Patient-derived organoids (PDOs) are valuable in predicting response to cancer therapy. PDOs are ideal models for precision oncologists. However, their practical application in guiding timely clinical decision...
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Article
Open AccessAssociation between toothbrushing and cardiovascular risk factors: a cross-sectional study using Korean National Health and Nutrition Examination Survey 2015–2017
Previous studies have suggested that frequent toothbrushing is associated with a lower risk of future cardiovascular events. We sought to investigate further the relationship between toothbrushing, cardiovascu...
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Article
Open AccessCorrection: Cancer organoid-based diagnosis reactivity prediction (CODRP) index-based anticancer drug sensitivity test in ALK-rearrangement positive non-small cell lung cancer (NSCLC)
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Open AccessCancer organoid-based diagnosis reactivity prediction (CODRP) index-based anticancer drug sensitivity test in ALK-rearrangement positive non-small cell lung cancer (NSCLC)
Recently, cancer organoid-based drug sensitivity tests have been studied to predict patient responses to anticancer drugs. The area under curve (AUC) or IC50 value of the dose-response curve (DRC) is used to diff...
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Article
Open AccessEnlarging pulmonary cyst: a rare form of alveolar adenoma
Alveolar adenoma is a rare benign tumour, usually presenting as a peripherally located solid mass, sometimes mimicking malignancy.
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Open AccessMetabolic profiles of lung adenocarcinoma via peripheral blood and diagnostic model construction
The metabolic profile of cancerous cells is shifted to meet the cellular demand required for proliferation and growth. Here we show the features of cancer metabolic profiles using peripheral blood of healthy c...
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Article
Shock Response of Precision Linear Shaped Charge in a Multistage Rocket System
Recently, a linear pyrotechnic device known as a precision linear shaped charge (PLSC) was proposed for the stage separation of a multistage rocket system. PLSCs exhibit improved system reliability by simplify...
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A Study on the Factors of Positive Psychological Capital on Organizational Citizenship Behavior: For Teachers of Infant Welfare Service Institutions
The purpose of this study is to identify the structural relationships among organizational identification, psychological well-being, and role performance and the moderating effect of the director's coaching le...
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Article
Open AccessStem cell laden nano and micro collagen/PLGA bimodal fibrous patches for myocardial regeneration
Although the use of cardiac patches is still controversial, cardiac patch has the significance in the field of the tissue engineered cardiac regeneration because it overcomes several shortcomings of intra-myoc...
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Article
Open AccessPhylogenetically diverse bacteria isolated from tattoo inks, an azo dye-rich environment, decolorize a wide range of azo dyes
There has been an interest in the microbial azo dye degradation as an optional method for the treatment of azo dye-containing wastes. Tattoo ink is an extremely unique azo dye-rich environment, which have neve...
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Exploring the Link Between Platelet Numbers and Vascular Homeostasis Across Early and Late Stages of Fibrosis in Hepatitis C
Thrombocytopenia is a hallmark of advanced liver disease. Platelets, growth factors (GFs), and vascular integrity are closely linked factors in disease pathogenesis, and their relationship, particularly in ear...
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Open AccessAnti-coccidial activity of the ethanol extract of Tribulus terrestris fruits on Eimeria tenella
Anti-coccidial effects of the fruits of Tribulus terrestris (Tribuli fructus) ethanol extract (TTE) were studied with animal experiment following per oral administration with Eimeria (E.) tenella. This experiment...
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Evaluation of Aneurysm Neck Angle Change After Endovascular Aneurysm Repair Clinical Investigations
To evaluate the aneurysm neck angle changes and post-endovascular aneurysm repair (EVAR) complications.
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Left Atrial and Left Ventricular Diastolic Function After the Maze Procedure for Atrial Fibrillation in Mitral Valve Disease: Degenerative Versus Rheumatic
The present study was aimed to compare the left atrial and left ventricular diastolic functions amongst the rheumatic and degenerative mitral valve disease patients in atrial fibrillation who reverted to norma...
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Article
Shape optimization of staggered ribs in a rotating equilateral triangular cooling channel
A rotating equilateral triangular cooling channel with staggered square ribs inside the leading edge of a turbine blade has been optimized in this work based on surrogate modeling. The fluid flow and heat tran...
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Multi-objective optimization of a guide vane in the turning region of a rotating U-duct to enhance heat transfer performance
An optimization has been performed for the design of a guide vane in the turning region of a rotating U-duct using the Kriging meta-model and a hybrid multi-objective evolutionary algorithm. Rotation of the U-...
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Anti-obesity and hypolipidemic effects of chufa (Cyperus esculentus L.) in mice fed a high-fat diet
This study was aimed to clarify the effect of defatted chufa (Cyperus esculentus L., DC) on diet-induced obesity and lipid metabolism in mice. C57BL/6J mice were fed 1 of 4 experimental diets for 7 weeks: a norma...
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Article
Insulin contributes to fine-tuning of the pancreatic beta-cell response to glucagon-like peptide-1
Glucagon-like peptide-1 (GLP-1) stimulates insulin secretion from pancreatic β-cells in a glucose-dependent manner. However, factors other than glucose that regulate the β-cell response to GLP-1 remain poorly ...
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Effects of the microstructure of ZnO seed layer on the ZnO nanowire density
In this study, we synthesized ZnO nanowires using Au catalytic particles formed on a ZnO seed layer. We modulated the microstructure of the ZnO seed layer by changing the sputtering power to investigate how th...
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Inhibitory activities of anthraquinones from Rubia akane on phosphatase regenerating liver-3
The methanolic extract of the roots of Rubia akane (Rubiaceae) was found to show inhibitory activity on phosphatase of regenerating liver-3 (PRL-3). Bioassay-guided fractionation of the methanolic extract resulte...