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1,067 Result(s)
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Article
Two Monte Carlo-based simulators for imaging-system modeling and projection simulation of flat-panel X-ray source
The advantages of a flat-panel X-ray source (FPXS) make it a promising candidate for imaging applications. Accurate imaging-system modeling and projection simulation are critical for analyzing imaging performa...
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Article
Open AccessPlastome evolution of Engelhardia facilitates phylogeny of Juglandaceae
Engelhardia (Juglandaceae) is a genus of significant ecological and economic importance, prevalent in the tropics and subtropics of East Asia. Although previous efforts based on multiple molecular markers providi...
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Valence-tailored copper-based nanoparticles for enhanced chemodynamic therapy through prolonged ROS generation and potentiated GSH depletion
Chemodynamic therapy (CDT), an inventive approach to cancer treatment, exploits innate chemical processes to trigger cell death through the generation of reactive oxygen species (ROS). While offering advantage...
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Arbuscular mycorrhizal fungi-mediated drought stress tolerance in kenaf (hibiscus cannabinus l.): a mechanistic approach
Drought is one of the important factors limiting crop growth. Plants can enhance resistance to various stressors by forming symbiotic relationships with arbuscular mycorrhizal fungi (AMF). However, the regulat...
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Exciting broadband thermochromic transmission property opposite to vanadium dioxide in the atmospheric window
The traditional telecommunications band performs poorly in harsh weather conditions due to atmospheric absorption. In recent years, researchers have begun to study optical communication through atmospheric win...
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Debris flow susceptibility and hazard assessment in Fushun based on hydrological response units
Fushun, located in Northeast China, is prone to debris flow disasters due to its complex topographical and geological conditions. In 2013, large-scale debris flow disasters triggered by a rainstorm broke out, ...
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Open AccessComparative genomic and transcriptomic analyses reveal distinct response strategies to hypoxia by Vibrio parahaemolyticus isolates of clinical and aquatic animal origins
Vibrio parahaemolyticus is a leading seafood borne pathogen worldwide. The aim of this study was to decipher the response mechanism of V. parahaemolyticus isolates of clinical and aquatic animal origins to the hy...
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Open AccessMeasurements of electroweak W±Z boson pair production in association with two jets in pp collisions at \( \sqrt{s} \) = 13 TeV with the ATLAS detector
Measurements of integrated and differential cross-sections for electroweak W±Z production in association with two jets (W±Zjj) in proton-proton collisions are presented. The data collected by the ATLAS detector a...
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Detecting the Bull’s-Eye Effect in Seismic Inversion Low-Frequency Models Using the Optimized YOLOv7 Model
To detect bull’s-eye anomalies in low-frequency seismic inversion models, the study proposed an advanced method using an optimized you only look once version 7 (YOLOv7) model. This model is enhanced by integratin...
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Open AccessUSP38 exacerbates pressure overload-induced left ventricular electrical remodeling
Ubiquitin-specific protease 38 (USP38), belonging to the USP family, is recognized for its role in controlling protein degradation and diverse biological processes. Ventricular arrhythmias (VAs) following hear...
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Article
Structural insights into somatostatin receptor 5 bound with cyclic peptides
Somatostatin receptor 5 (SSTR5) is highly expressed in ACTH-secreting pituitary adenomas and is an important drug target for the treatment of Cushing’s disease. Two cyclic SST analog peptides (pasireotide and ...
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Multidisciplinary and multiscale nanoscience research roadmap based on large scientific facilities
With the advancement of modern science and technology, large scientific facilities are increasingly oriented toward demand and application, and can be used for basic research as well as serving multiple discip...
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Unveiling the impact of cirrhotic cardiomyopathy on portal hemodynamics and survival after transjugular intrahepatic portosystemic shunt: a prospective study
The placement of Transjugular intrahepatic portosystemic shunt (TIPS) results in a sudden increase in central circulating blood volume, which requires proper regulation of the cardiovascular system. We aimed t...
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Kv3.1 Interaction with UBR5 Is Required for Chronic Inflammatory Pain
Chronic inflammatory pain caused by neuronal hyperactivity is a common and refractory disease. Kv3.1, a member of the Kv3 family of voltage-dependent K+ channels, is a major determinant of the ability of neurons ...
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A novel FAK-degrading PROTAC molecule exhibited both anti-tumor activities and efficient MDR reversal effects
FAK (focal adhesion kinase) is widely involved in cancer growth and drug resistance development. Thus, FAK inhibition has emerged as an effective strategy for tumor treatment both as a monotherapy or in combin...
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Open AccessMechanistic prediction and validation of Brevilin A Therapeutic effects in Lung Cancer
Traditional Chinese medicine (TCM) has been found widespread application in neoplasm treatment, yielding promising therapeutic candidates. Previous studies have revealed the anti-cancer properties of Brevilin ...
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A state-of-the-art review on delayed expansion of cemented paste backfill materials
Utilizing delayed expansion cemented paste backfill materials (DECPB) in mine backfill operations offers an effective solution to the challenge of achieving proper contact between the in-situ cemented backfill...
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Open AccessAdvances in the isolation, cultivation, and identification of gut microbes
The gut microbiome is closely associated with human health and the development of diseases. Isolating, characterizing, and identifying gut microbes are crucial for research on the gut microbiome and essential ...
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Open AccessA comparative plastome approach enhances the assessment of genetic variation in the Melilotus genus
Melilotus, a member of the Fabaceae family, is a pivotal forage crop that is extensively cultivated in livestock regions globally due to its notable productivity and ability to withstand abiotic stress. However, ...
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Narrow gap welding of 316L thick-section steel with cold metal transition pulsed arc swing
Narrow gap welding of 316L stainless steel thick plate was carried out using the cold metal transition pulsed wire-arc swing method. The effects of heat input, arc swing, and shielding mode on weld sha** and...