5 Result(s)
within
Mel Krajden
Medical Microbiology
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Article
Open AccessFactors associated with SARS-CoV-2 infection in unvaccinated children and young adults
Pediatric COVID-19 cases are often mild or asymptomatic, which has complicated estimations of disease burden using existing testing practices. We aimed to determine the age-specific population seropositivity a...
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Article
Open AccessGlobal phylogeny of Treponema pallidum lineages reveals recent expansion and spread of contemporary syphilis
Syphilis, which is caused by the sexually transmitted bacterium Treponema pallidum subsp. pallidum, has an estimated 6.3 million cases worldwide per annum. In the past ten years, the incidence of syphilis has inc...
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Article
HIV serology signal-to-cutoff ratio as a rapid method to predict confirmation of HIV infection
Early and rapid detection of patients with HIV is a key to preventing further transmission. The purpose of this study was to assess the ability of signal-to-cutoff (S/CO) ratio from initial screening fourth-ge...
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Article
Open AccessTreatment outcomes for isoniazid-resistant tuberculosis under program conditions in British Columbia, Canada
Every year, over 1 million people develop isoniazid (INH) resistant tuberculosis (TB). Yet, the optimal treatment regimen remains unclear. Given increasing prevalence, the clinical efficacy of regimens used by...
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Article
Open AccessTwin epidemics of new and prevalent hepatitis C infections in Canada: BC Hepatitis Testers Cohort
We characterized the twin epidemics of new and prevalent hepatitis C virus (HCV) infections in British Columbia, Canada to inform prevention, care and treatment programs.
