6 Result(s)
within
Md. Zubbair Malik
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessDynamical states, possibilities and propagation of stress signal
The stress driven dynamics of Notch-Wnt-p53 cross-talk is subjected to a few possible dynamical states governed by simple fractal rules, and allowed to decide its own fate by choosing one of these states which...
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Article
Open AccessAssessment of the key regulatory genes and their Interologs for Turner Syndrome employing network approach
Turner Syndrome (TS) is a condition where several genes are affected but the molecular mechanism remains unknown. Identifying the genes that regulate the TS network is one of the main challenges in understandi...
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Article
Open AccessIdentification of key regulators in prostate cancer from gene expression datasets of patients
Identification of key regulators and regulatory pathways is an important step in the discovery of genes involved in cancer. Here, we propose a method to identify key regulators in prostate cancer (PCa) from a ...
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Article
Open AccessTransition and identification of pathological states in p53 dynamics for therapeutic intervention
We study a minimal model of the stress-driven p53 regulatory network that includes competition between active and mutant forms of the tumor-suppressor gene p53. Depending on the nature and level of the externa...
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Article
Open AccessIdentification of key regulators in Sarcoidosis through multidimensional systems biological approach
Sarcoidosis is a multi-organ disorder where immunology, genetic and environmental factors play a key role in causing Sarcoidosis, but its molecular mechanism remains unclear. Identification of its genetics pro...
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Article
Open AccessA bioinformatics approach to elucidate conserved genes and pathways in C. elegans as an animal model for cardiovascular research
Cardiovascular disease (CVD) is a collective term for disorders of the heart and blood vessels. The molecular events and biochemical pathways associated with CVD are difficult to study in clinical settings on ...
