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Article
Open AccessGlycolaldehyde-modified proteins cause adverse functional and structural aortic remodeling leading to cardiac pressure overload
Growing evidence supports the role of advanced glycation end products (AGEs) in the development of diabetic vascular complications and cardiovascular diseases (CVDs). We have shown that high-molecular-weight A...
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Article
Open AccessHigh intensity training improves cardiac function in healthy rats
Exercise training is a low cost and safe approach for reducing the risk of cardiovascular disease development. Currently, moderate-intensity training (MIT) is the most preferred exercise type. However, high-in...
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Article
Open AccessPyridoxamine improves survival and limits cardiac dysfunction after MI
Advanced glycation end products (AGEs) play a key role in the progression of heart failure. Whether treatments limiting AGEs formation would prevent adverse left ventricular remodeling after myocardial infarct...