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  1. Article

    Open Access

    Artificial intelligence-derived neurofibrillary tangle burden is associated with antemortem cognitive impairment

    Tauopathies are a category of neurodegenerative diseases characterized by the presence of abnormal tau protein-containing neurofibrillary tangles (NFTs). NFTs are universally observed in aging, occurring with ...

    Gabriel A. Marx, Daniel G. Koenigsberg in Acta Neuropathologica Communications (2022)

  2. Article

    Open Access

    Antemortem detection of Parkinson’s disease pathology in peripheral biopsies using artificial intelligence

    The diagnosis of Parkinson’s disease (PD) is challenging at all stages due to variable symptomatology, comorbidities, and mimicking conditions. Postmortem assessment remains the gold standard for a definitive ...

    Maxim Signaevsky, Bahram Marami, Marcel Prastawa in Acta Neuropathologica Communications (2022)