6 Result(s)
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Article
Isolated childhood growth hormone deficiency: a 30-year experience on final height and a new prediction model
We aimed to evaluate the near-final height (nFHt) in a large cohort of pediatricpatients with growth hormone deficiency (GHD) and to elaborate a new predictive method of nFHt.
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Article
Efficacy of long-term growth hormone therapy in short children with reduced growth hormone biological activity
Aim: The optimal GH regimen, in terms of cost-effectiveness, in children with normal GH immunoreactivity but reduced bioactivity is still debated. Methods: In 12 GH-deficient (GHD) and 12 bioinac...
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Article
Growth Hormone Immunoreactivity Does Not Reflect Bioactivity
In childhood, the largest secretory burst of GH occurs during nighttime, and consists of a complex mixture of molecular forms of GH that are thought to have different biologic activity. Standard GH assays cann...
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Article
Circulating GH Isoforms and GH Bioactivity in Preterm Neonates
Among the molecular variants of human GH, the monomeric 22-kD is the predominant isoform, whereas the 20-kD is the second most abundant isoform. Because little is known on the pattern of human GH isoforms in t...
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Article
95 NEONATAL EVOLUTION OF IGFs AND SERUM THYMIDINE ACTIVITY
Serum growth-promoting activity measured as 3H-THY incorporation into lymphocytes (TA) was measured simultaneously with RIA of IGFs I and II in the same samples of cord blood and of capillary blood collected 3...
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Article
Serum Growth-Promoting Activity Measured as [3H]Thymidine Incorporation into Human Activated Lymphocytes and Serum Transferrin Levels in Newborns and Mothers
ABSTRACT: Serum growth-promoting activity measured as [3H]thymidine incorporation into human activated lymphocytes and serum transferrin levels were measured during the perinatal period in newborns and mothers. B...
