45 Result(s)
within
Matthew R. Cooperberg
English
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Article
High-risk prostate cancer in the United States, 1990–2007
This study aimed to describe national trends in presentation, management, and outcomes for men with high risk prostate cancer.
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Chapter
Quality of Care Indicators for Radical Cystectomy
Radical cystectomy is the gold standard treatment for invasive bladder cancer, and requires high standards for both surgical skill and ancillary support to achieve consistently good outcomes. As is the case el...
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Article
Open AccessElectronic patient self-assessment and management (SAM): a novel framework for cancer survivorship
We propose a novel framework for management of cancer survivorship: electronic patient Self-Assessment and Management (SAM). SAM is a framework for transfer of information to and from patients in such a way as...
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Article
Gender differences in subcutaneous and perirenal fat distribution
Body mass index (BMI) has been shown to influence the outcome of various surgical procedures. The purpose of this study is to assess the relationship between BMI, gender, and the distribution of subcutaneous a...
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Chapter
Robot-Assisted Radical Prostatectomy: A Prostate Surgeon’s Perspective
The availability and promulgation of robotic technology has resulted in a paradigm shift for radical prostatectomy. Historically radical prostatectomy was performed using an open approach, usually the retropub...
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Article
Open AccessThe example of CaPSURE: lessons learned from a national disease registry
Although randomized controlled trials (RCTs) remain the gold standard for determining evidence-based clinical practices, large disease registries that enroll large numbers of patients have become paramount as ...
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Article
For localized prostate cancer, does technology equal progress?
Recent evolution of prostate cancer treatment reflects technological arms races driven by economic incentives rather than high-quality evidence—as exemplified by proton-beam radiation, recently found markedly ...
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Article
New types of radiotherapy improve cancer outcome but at what cost?
New and very expensive forms of radiotherapy, such as intensity-modulated radiation therapy and proton therapy, have taken over the localized prostate cancer market. But is there enough evidence to justify the...
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Article
Risk-Based Prostate Cancer Screening: Who and How?
The purpose of this review is to identify clinical risk factors for prostate cancer and to assess the utility and limitations of our current tools for prostate cancer screening. Prostate-specific antigen is th...
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Article
Implications of the New AUA Guidelines on Prostate Cancer Detection in the U.S.
In 2012, the U.S. Preventive Services Task Force (USPSTF) issued a blanket “D” recommendation against all prostate-specific antigen (PSA)-based early detection efforts for prostate cancer, reflecting critical ...
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Article
A new look at prostate cancer treatment complications
A recent population-based analysis from Nam and coauthors found high complication rates occurring within 5 years of prostatectomy or radiation therapy interventions for prostate cancer. These findings emphasiz...
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Article
Long-term follow-up of International Prostate Symptom Score (IPSS) in men following prostate brachytherapy
To investigate variation in the International Prostate Symptom Score (IPSS) in men following prostate brachytherapy.
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Article
Clinical Utility of Biomarkers in Localized Prostate Cancer
A new generation of prostate cancer (PCa) biomarkers has emerged, including diagnostic serum and urine markers aimed at refining the identification high-grade tumors and tissue-based gene expression assays off...
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Article
Why the prostate arm of the PLCO trial failed and what it has taught us
Given a recent update from the PLCO trial reporting that over 90% of men in the 'usual care' arm underwent some degree of PSA testing, the PLCO can no longer accurately be called a trial of screening versus no...
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Article
Epidemiology of prostate cancer
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Chapter
Prostate Cancer Markers
Diagnostic biomarkers derived from blood, urine, or prostate tissue provide additional information beyond clinical calculators to determine the risk of detecting high-grade prostate cancer. Once diagnosed, m...
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Article
The use of PET/CT in prostate cancer
Positron emission tomography/computed tomography (PET/CT) has recently emerged as a promising diagnostic imaging platform for prostate cancer. Several radiolabelled tracers have demonstrated efficacy for cance...
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Article
Neutrophil, lymphocyte and platelet counts, and risk of prostate cancer outcomes in white and black men: results from the SEARCH database
Systemic inflammation, as measured by C-reactive protein, has been linked with poor prostate cancer (PC) outcomes, predominantly in white men. Whether other immune measures like white blood cell counts are cor...
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Article
Open AccessHigh-throughput, Efficient, and Unbiased Capture of Small RNAs from Low-input Samples for Sequencing
MicroRNAs hold great promise as biomarkers of disease. However, there are few efficient and robust methods for measuring microRNAs from low input samples. Here, we develop a high-throughput sequencing protocol...
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Article
Practice patterns of primary EBRT with and without ADT in prostate cancer treatment
Androgen deprivation therapy (ADT) has been shown to improve survival for men with intermediate and high-risk prostate cancer undergoing external-beam radiation therapy (EBRT). Using data from a community-base...
