15 Result(s)
within
Matthew R. Cooperberg
English
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Article
Open AccessPatient and physician perspectives on treatments for low-risk prostate cancer: a qualitative study
Patients diagnosed with low-risk prostate cancer (PCa) are confronted with a difficult decision regarding whether to undergo definitive treatment or to pursue an active surveillance protocol. This is potential...
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Correction to: Prostate volume, baseline urinary function, and their association with treatment choice and post-treatment urinary function in men treated for localized prostate cancer
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Open AccessThe natural history of a delayed detectable PSA after radical prostatectomy
Men with a detectable PSA after radical prostatectomy (RP) are often offered salvage therapy while those with an undetectable PSA are monitored. We aim to better characterize the natural history of men with an...
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The state of focal therapy in the treatment of prostate cancer: the university of California collaborative (UC-Squared) consensus statement
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Open AccessExplainable ML models for a deeper insight on treatment decision for localized prostate cancer
Although there are several decision aids for the treatment of localized prostate cancer (PCa), there are limitations in the consistency and certainty of the information provided. We aimed to better understand ...
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Correction to: Association between adherence to radiation therapy quality metrics and patient reported outcomes in prostate cancer
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Open AccessActive surveillance in intermediate-risk prostate cancer with PSA 10–20 ng/mL: pathological outcome analysis of a population-level database
Active surveillance (AS) is generally recognized as the preferred option for men with low-risk prostate cancer. Current guidelines use prostate-specific antigen (PSA) of 10–20 ng/mL or low-volume biopsy Gleaso...
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Open AccessAccommodating heterogeneous missing data patterns for prostate cancer risk prediction
We compared six commonly used logistic regression methods for accommodating missing risk factor data from multiple heterogeneous cohorts, in which some cohorts do not collect some risk factors at all, and deve...
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Open AccessSingle-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states
Prostate cancer is the second most common malignancy in men worldwide and consists of a mixture of tumor and non-tumor cell types. To characterize the prostate cancer tumor microenvironment, we perform single-...
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Open AccessSurvival of African-American and Caucasian men after sipuleucel-T immunotherapy: outcomes from the PROCEED registry
African Americans experience greater prostate cancer risk and mortality than do Caucasians. An analysis of pooled phase III data suggested differences in overall survival (OS) between African American and Cauc...
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Open AccessDecipher identifies men with otherwise clinically favorable-intermediate risk disease who may not be good candidates for active surveillance
We aimed to validate Decipher to predict adverse pathology (AP) at radical prostatectomy (RP) in men with National Comprehensive Cancer Network (NCCN) favorable-intermediate risk (F-IR) prostate cancer (PCa), ...
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Open AccessHigh-throughput, Efficient, and Unbiased Capture of Small RNAs from Low-input Samples for Sequencing
MicroRNAs hold great promise as biomarkers of disease. However, there are few efficient and robust methods for measuring microRNAs from low input samples. Here, we develop a high-throughput sequencing protocol...
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Epidemiology of prostate cancer
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Open AccessThe example of CaPSURE: lessons learned from a national disease registry
Although randomized controlled trials (RCTs) remain the gold standard for determining evidence-based clinical practices, large disease registries that enroll large numbers of patients have become paramount as ...
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Open AccessElectronic patient self-assessment and management (SAM): a novel framework for cancer survivorship
We propose a novel framework for management of cancer survivorship: electronic patient Self-Assessment and Management (SAM). SAM is a framework for transfer of information to and from patients in such a way as...
