15 Result(s)
within
Matthew R. Cooperberg
English
Oncology
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Article
Open AccessPatient and physician perspectives on treatments for low-risk prostate cancer: a qualitative study
Patients diagnosed with low-risk prostate cancer (PCa) are confronted with a difficult decision regarding whether to undergo definitive treatment or to pursue an active surveillance protocol. This is potential...
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Article
Are associations between obesity and prostate cancer outcomes following radical prostatectomy the same in smokers and non-smokers? Results from the SEARCH Cohort
Obesity and smoking have been associated with poor prostate cancer (PC) outcomes. We investigated associations between obesity and biochemical recurrence (BCR), metastasis, castrate resistant-PC (CRPC), PC-spe...
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Article
Emulation of a target trial with sustained treatment strategies: an application to prostate cancer using both inverse probability weighting and the g-formula
As with many chronic illnesses, recurrent prostate cancer generally requires sustained treatment to prolong survival. However, initiating treatment immediately after recurrence may negatively impact quality of...
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Article
Monocyte counts and prostate cancer outcomes in white and black men: results from the SEARCH database
Circulating inflammatory markers may predict prostate cancer (PC) outcomes. For example, a recent study showed that higher peripheral blood monocyte counts were associated with aggressive PC in Asian men under...
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Article
First-year weight loss with androgen-deprivation therapy increases risks of prostate cancer progression and prostate cancer-specific mortality: results from SEARCH
We aimed to study the associations between androgen-deprivation therapy (ADT)-induced weight changes and prostate cancer (PC) progression and mortality in men who had undergone radical prostatectomy (RP).
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Article
Neutrophil, lymphocyte and platelet counts, and risk of prostate cancer outcomes in white and black men: results from the SEARCH database
Systemic inflammation, as measured by C-reactive protein, has been linked with poor prostate cancer (PC) outcomes, predominantly in white men. Whether other immune measures like white blood cell counts are cor...
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Chapter
Prostate Cancer Markers
Diagnostic biomarkers derived from blood, urine, or prostate tissue provide additional information beyond clinical calculators to determine the risk of detecting high-grade prostate cancer. Once diagnosed, m...
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Article
Epidemiology of prostate cancer
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Article
Clinical Utility of Biomarkers in Localized Prostate Cancer
A new generation of prostate cancer (PCa) biomarkers has emerged, including diagnostic serum and urine markers aimed at refining the identification high-grade tumors and tissue-based gene expression assays off...
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Article
Long-term follow-up of International Prostate Symptom Score (IPSS) in men following prostate brachytherapy
To investigate variation in the International Prostate Symptom Score (IPSS) in men following prostate brachytherapy.
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Article
A new look at prostate cancer treatment complications
A recent population-based analysis from Nam and coauthors found high complication rates occurring within 5 years of prostatectomy or radiation therapy interventions for prostate cancer. These findings emphasiz...
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Article
For localized prostate cancer, does technology equal progress?
Recent evolution of prostate cancer treatment reflects technological arms races driven by economic incentives rather than high-quality evidence—as exemplified by proton-beam radiation, recently found markedly ...
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Article
Open AccessThe example of CaPSURE: lessons learned from a national disease registry
Although randomized controlled trials (RCTs) remain the gold standard for determining evidence-based clinical practices, large disease registries that enroll large numbers of patients have become paramount as ...
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Chapter
Quality of Care Indicators for Radical Cystectomy
Radical cystectomy is the gold standard treatment for invasive bladder cancer, and requires high standards for both surgical skill and ancillary support to achieve consistently good outcomes. As is the case el...
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Article
High-risk prostate cancer in the United States, 1990–2007
This study aimed to describe national trends in presentation, management, and outcomes for men with high risk prostate cancer.
