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  1. No Access

    Article

    Large-scale discovery of enhancers from human heart tissue

    Len Pennacchio, Axel Visel and colleagues use an epigenomic approach to identify a large number of candidate enhancers from human heart tissue. This work will facilitate further studies into the role of enhanc...

    Dalit May, Matthew J Blow, Tommy Kaplan, David J McCulley… in Nature Genetics (2012)

  2. No Access

    Article

    ChIP-Seq identification of weakly conserved heart enhancers

    Len Pennacchio and colleagues used ChIP-Seq with the enhancer-associated protein p300 to identify 3,000 candidate cardiac transcriptional enhancers in embryonic mice at E11.5. Notably, most candidate heart enh...

    Matthew J Blow, David J McCulley, Zirong Li, Tao Zhang… in Nature Genetics (2010)

  3. Article

    Open Access

    RNA editing of human microRNAs

    MicroRNAs (miRNAs) are short RNAs of around 22 nucleotides that regulate gene expression. The primary transcripts of miRNAs contain double-stranded RNA and are therefore potential substrates for adenosine to i...

    Matthew J Blow, Russell J Grocock, Stijn van Dongen, Anton J Enright… in Genome Biology (2006)

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