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    Article

    Map** the microbiome milieu

    This month’s Genome Watch discusses the application of spatial transcriptomics to investigate the arrangements of microbial communities and their effects on the host.

    Matthew J. Blow in Nature Reviews Microbiology (2024)

  2. Article

    Open Access

    Topologically associating domain boundaries are required for normal genome function

    Topologically associating domain (TAD) boundaries partition the genome into distinct regulatory territories. Anecdotal evidence suggests that their disruption may interfere with normal gene expression and caus...

    Sudha Rajderkar, Iros Barozzi, Yiwen Zhu, Rong Hu, Yanxiao Zhang in Communications Biology (2023)

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    Article

    Persistence and plasticity in bacterial gene regulation

    Organisms orchestrate cellular functions through transcription factor (TF) interactions with their target genes, although these regulatory relationships are largely unknown in most species. Here we report a hi...

    Leo A. Baumgart, Ji Eun Lee, Asaf Salamov, David J. Dilworth, Hyunsoo Na in Nature Methods (2021)

  4. Article

    Open Access

    Resequencing and annotation of the Nostoc punctiforme ATTC 29133 genome: facilitating biofuel and high-value chemical production

    Cyanobacteria have the potential to produce bulk and fine chemicals and members belonging to Nostoc sp. have received particular attention due to their relatively fast growth rate and the relative ease with whic...

    Luis E. Moraes, Matthew J. Blow, Erik R. Hawley, Hailan Piao, Rita Kuo in AMB Express (2017)

  5. Article

    Open Access

    RNA editing of human microRNAs

    MicroRNAs (miRNAs) are short RNAs of around 22 nucleotides that regulate gene expression. The primary transcripts of miRNAs contain double-stranded RNA and are therefore potential substrates for adenosine to i...

    Matthew J Blow, Russell J Grocock, Stijn van Dongen, Anton J Enright in Genome Biology (2006)