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Article
Map** the microbiome milieu
This month’s Genome Watch discusses the application of spatial transcriptomics to investigate the arrangements of microbial communities and their effects on the host.
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Open AccessTopologically associating domain boundaries are required for normal genome function
Topologically associating domain (TAD) boundaries partition the genome into distinct regulatory territories. Anecdotal evidence suggests that their disruption may interfere with normal gene expression and caus...
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Article
Persistence and plasticity in bacterial gene regulation
Organisms orchestrate cellular functions through transcription factor (TF) interactions with their target genes, although these regulatory relationships are largely unknown in most species. Here we report a hi...
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Article
Open AccessResequencing and annotation of the Nostoc punctiforme ATTC 29133 genome: facilitating biofuel and high-value chemical production
Cyanobacteria have the potential to produce bulk and fine chemicals and members belonging to Nostoc sp. have received particular attention due to their relatively fast growth rate and the relative ease with whic...
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Open AccessRNA editing of human microRNAs
MicroRNAs (miRNAs) are short RNAs of around 22 nucleotides that regulate gene expression. The primary transcripts of miRNAs contain double-stranded RNA and are therefore potential substrates for adenosine to i...