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  1. Article

    Open Access

    Irinophore C™, a lipid nanoparticle formulation of irinotecan, abrogates the gastrointestinal effects of irinotecan in a rat model of clinical toxicities

    Irinotecan is a water-soluble camptothecin derivative with clinical activity against colorectal and small cell lung cancers and is currently a standard of care therapeutic in the treatment of colorectal cancer...

    Dawn N. Waterhouse, Brent W. Sutherland, Nancy Dos Santos… in Investigational New Drugs (2014)

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