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  1. Article

    Open Access

    The serotonin receptor 3E variant is a risk factor for female IBS-D

    Irritable bowel syndrome (IBS) is a gut-brain disorder of multifactorial origin. Evidence of disturbed serotonergic function in IBS accumulated for the 5-HT3 receptor family. 5-HT3Rs are encoded by HTR3 genes and...

    Nikola Fritz, Sabrina Berens, Yuanjun Dong in Journal of Molecular Medicine (2022)

  2. Article

    Open Access

    World Congress Integrative Medicine & Health 2017: part two

    Carolyn Ee, Sharmala Thuraisingam in BMC Complementary and Alternative Medicine (2017)

  3. Article

    Guidelines on the management of IgE-mediated food allergies

    Prof. Dr. Margitta Worm, Imke Reese, Barbara Ballmer-Weber in Allergo Journal International (2015)

  4. Article

    Allergen and allergy risk assessment, allergen management, and gaps in the European Food Information Regulation (FIR)

    Individuals suffering from IgE-mediated food allergies are obliged to systematically eliminate the culprit allergen from their diet. To support allergic consumers in avoiding food allergens to make informed an...

    Dr. Imke Reese, Thomas Holzhauser, Sabine Schnadt in Allergo Journal International (2015)

  5. Article

    Open Access

    Excretion of urinary histamine and N-tele methylhistamine in patients with gastrointestinal food allergy compared to non-allergic controls during an unrestricted diet and a hypoallergenic diet

    Patients with gastrointestinal food allergy are characterised by increased production of mast cell derived mediators upon allergen contact and present often with unspecific symptoms. The aim of this study was ...

    Martin Raithel, Alexander Hagel, Heinz Albrecht, Yurdaguel Zopf in BMC Gastroenterology (2015)

  6. No Access

    Chapter and Conference Paper

    Panorama Map** of the Esophagus from Gastroscopic Video

    For the examination and clinical assessment of the esophagus, video endoscopy is applied. Video clips and still images are generated along these procedures which are then used for routine documentation. Due to...

    Martin Prinzen, Martin Raithel, Tobias Bergen in Bildverarbeitung für die Medizin 2015 (2015)

  7. No Access

    Article

    Outcome and complications of endoscopic balloon dilatations in various types of ileocaecal and colonic stenosis in patients with Crohn’s disease

    We examined the outcome and the complications of endoscopic balloon dilatation (EBD) of ileocaecal and colonic strictures due to Crohn’s disease.

    Alexander F. Hagel, Anna Hahn, Wolfgang Dauth, Klaus Matzel in Surgical Endoscopy (2014)

  8. Article

    Open Access

    Eosinophilic gastroenteritis with refractory ulcer disease and gastrointestinal bleeding as a rare manifestation of seronegative gastrointestinal food allergy

    Gastrointestinal bleeding and iron deficiency anaemia may cause severe symptoms and may require extensive diagnostics and substantial amounts of health resources.

    Martin Raithel, Markus Hahn, Konrad Donhuijsen, Alexander F Hagel in Nutrition Journal (2014)

  9. No Access

    Article

    Food allergies resulting from immunological cross-reactivity with inhalant allergens

    A large proportion of immunoglobulin E (IgE)-mediated food allergies in older children, adolescents and adults are caused by cross-reactive allergenic structures. Primary sensitization is most commonly to inha...

    Prof. Dr. Margitta Worm, Uta Jappe, Jörg Kleine-Tebbe in Allergo Journal International (2014)

  10. Article

    Open Access

    Osteonecrosis of the jaw in a Crohn’s disease patient following a course of Bisphosphonate and Adalimumab therapy: a case report

    Bisphosphonates have a widespread indication for osteoporosis and are also applied in cancer patients with skeletal-related conditions. Bisphosphonate-associated osteonecrosis of the jaw (BRONJ) is a feared si...

    Raimund HM Preidl, Tobias Ebker, Martin Raithel, Falk Wehrhan in BMC Gastroenterology (2014)

  11. No Access

    Article

    Intravenous infusion of ascorbic acid decreases serum histamine concentrations in patients with allergic and non-allergic diseases

    Histamine plays an important role in the development of symptoms in allergic, infectious, neoplastic and other diseases. Empirical findings have suggested beneficial effects of ascorbic acid supplementation in...

    Alexander F. Hagel, Christian M. Layritz in Naunyn-Schmiedeberg's Archives of Pharmaco… (2013)

  12. No Access

    Article

    Activation of the transcription factor Nrf2 in macrophages, Caco-2 cells and intact human gut tissue by Maillard reaction products and coffee

    In addition to direct antioxidative effects, Maillard reaction products (MRPs) could increase the antioxidative capacity of cells through the induction of cytoprotective enzymes. Since many of those enzymes ar...

    Tanja Sauer, Martin Raithel, Jürgen Kressel, Gerald Münch in Amino Acids (2013)

  13. No Access

    Article

    Over-the-Scope Clip Application Yields a High Rate of Closure in Gastrointestinal Perforations and May Reduce Emergency Surgery

    Perforation of the gastrointestinal tract may cause various complications and may require emergency surgery, even in patients with significant comorbidities.

    Alexander Fritzkarl Hagel, Andreas Naegel in Journal of Gastrointestinal Surgery (2012)

  14. Article

    Open Access

    Chronic calcium pyrophosphate crystal inflammatory arthritis induced by extreme hypomagnesemia in short bowel syndrome

    Short bowel syndrome (SBS) may induce a plethora of clinical symptoms ranging from underweight to nutrient-, vitamin- and electrolyte deficiencies. The objective of this case report is to illustrate how demand...

    Markus Hahn, Martin Raithel, Alexander Hagel, Teresa Biermann in BMC Gastroenterology (2012)

  15. No Access

    Article

    Decreased Histamine Catabolism in the Colonic Mucosa of Patients with Colonic Adenoma

    Alterations in mucosal histamine degradation play an important role in various gastrotinestinal diseases including colonic adenoma. In humans, histamine can be catabolized either by oxidative deamination by di...

    Michael A. Kuefner, Hubert G. Schwelberger in Digestive Diseases and Sciences (2008)

  16. No Access

    Article

    Activation of NFκB Represents the Central Event in the Neoplastic Progression Associated with Barrett's Esophagus: A Possible Link to the Inflammation and Overexpression of COX-2, PPARγ and Growth Factors

    The molecular mechanisms responsible for the progression of malignant transformation in Barrett's esophagus (BE) are still poorly understood. This study was undertaken (1) to investigate the gene and protein e...

    Peter C. Konturek, Agnieszka Nikiforuk, Joanna Kania in Digestive Diseases and Sciences (2004)