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    Article

    Design, synthesis and anti-mycobacterial evaluation of some new N-phenylpyrazine-2-carboxamides

    N-Phenylpyrazine-2-carboxamides (anilides of pyrazinoic acids with simple substituents in various positions) were previously shown to possess significant biological activities in vitro, markedly anti-mycobacter.....

    Jan Zitko, Barbora Servusová-Vaňásková, Pavla Paterová in Chemical Papers (2016)

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    Article

    Preparation and antiplatelet activity of glycidic acid derivatives

    Arylalkanoic acid derivatives exhibit a variety of biological effects. In the current publication some of new glycidic acid derivatives were prepared via the Darzens condensation. The synthetic approach, analy...

    Josef Jampílek, Eliška Brojerová, Martin Doležal, Jiří Kuneš, Daniel Jun in Chemical Papers (2008)

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    Article

    Determination of the Lipophilicity of Potential Antituberculotic Compounds by RP-TLC

    RP-TLC retention behavior has been studied for a series of potential antituberculotic drugs from a group of substituted anilides of pyrazine-2-carboxylic acid. Lipophilicity was determined by use of reversed-p...

    Zlata Mrkvičková, Petra Kovaříková in JPC – Journal of Planar Chromatography – M… (2006)