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Article
Design, synthesis and anti-mycobacterial evaluation of some new N-phenylpyrazine-2-carboxamides
N-Phenylpyrazine-2-carboxamides (anilides of pyrazinoic acids with simple substituents in various positions) were previously shown to possess significant biological activities in vitro, markedly anti-mycobacter.....
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Article
Preparation and antiplatelet activity of glycidic acid derivatives
Arylalkanoic acid derivatives exhibit a variety of biological effects. In the current publication some of new glycidic acid derivatives were prepared via the Darzens condensation. The synthetic approach, analy...
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Article
Determination of the Lipophilicity of Potential Antituberculotic Compounds by RP-TLC
RP-TLC retention behavior has been studied for a series of potential antituberculotic drugs from a group of substituted anilides of pyrazine-2-carboxylic acid. Lipophilicity was determined by use of reversed-p...