2 Result(s)
within
Mart Saarma
Antibodies
Biochemistry, general
Cell Biology
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Article
Open AccessDeficiency of the ER-stress-regulator MANF triggers progressive outer hair cell death and hearing loss
The non-conventional neurotrophic factor mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER)-resident protein that promotes ER homeostasis. MANF has a cytoprotective fun...
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Article
Open AccessAugmenting hematoma-scavenging capacity of innate immune cells by CDNF reduces brain injury and promotes functional recovery after intracerebral hemorrhage
During intracerebral hemorrhage (ICH), hematoma formation at the site of blood vessel damage results in local mechanical injury. Subsequently, erythrocytes lyse to release hemoglobin and heme, which act as neu...
