5 Result(s)
within
Markku Saloheimo
Biomedical Engineering/Biotechnology
Biotechnology
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Article
Open AccessComparison of intracellular and secretion-based strategies for production of human α-galactosidase A in the filamentous fungus Trichoderma reesei
Trichoderma reesei is known as a good producer of industrial proteins but has hitherto been less successful in the production of therapeutic proteins. In order to elucidate the bottlenecks of heterologous protein...
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Article
Correction: Corrigendum: Genome sequencing and analysis of the biomass-degrading fungus Trichoderma reesei (syn. Hypocrea jecorina)
Nat. Biotechnol. 26, 553–560 (2008); published online 4 May 2008; corrected after print 9 October 2008. In the version of this article initially published, an author's name was misspelled as Barbote. The corre...
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Article
Open AccessGenome sequencing and analysis of the biomass-degrading fungus Trichoderma reesei (syn. Hypocrea jecorina)
Trichoderma reesei is the main industrial source of cellulases and hemicellulases used to depolymerize biomass to simple sugars that are converted to chemical intermediates and biofuels, such as ethanol. We assem...
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Article
Open AccessPhysiological evaluation of the filamentous fungus Trichoderma reesei in production processes by marker gene expression analysis
Biologically relevant molecular markers can be used in evaluation of the physiological state of an organism in biotechnical processes. We monitored at high frequency the expression of 34 marker genes in batch,...
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Article
Heterologous Production of a Ligninolytic Enzyme: Expression of the Phlebia Radiata Laccase Gene in Trichoderma Reesei
We have expressed a gene encoding the ligninolytic laccase enzyme of the white–rot fungus Phlebia radiata in the soft rot fungus Trichoderma reesei under the promoter of the major cellulase gene (cbh1). Construct...
