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Resolving Multicopy Duplications de novo Using Polyploid Phasing

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    Open Access

    Map** single molecule sequencing reads using basic local alignment with successive refinement (BLASR): application and theory

    Recent methods have been developed to perform high-throughput sequencing of DNA by Single Molecule Sequencing (SMS). While Next-Generation sequencing methods may produce reads up to several hundred bases long,...

    Mark J Chaisson, Glenn Tesler in BMC Bioinformatics (2012)

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