10 Result(s)
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Article
Open AccessJuvenile dermatomyositis: association between nail fold capillary end row loop– area under the curve– and disease damage indicators
Juvenile Dermatomyositis (JDM) is a rare autoimmune disease characterized by skin and muscle inflammation. The loss of nail fold capillary end row loops (ERL) is evidence of small vessel involvement in JDM. Th...
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Open AccessNailfold capillary density in 140 untreated children with juvenile dermatomyositis: an indicator of disease activity
We lack a reliable indicator of disease activity in Juvenile Dermatomyositis (JDM), a rare disease. The goal of this study is to identify the association of nailfold capillary End Row Loop (ERL) loss with dise...
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Article
Open AccessRituximab-associated Hypogammaglobulinemia in pediatric patients with autoimmune diseases
Despite the increased use of rituximab in treating pediatric patients with autoimmune diseases in the last decade, there are limited data on rituximab safety in those subjects who have a develo** immune syst...
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Urine biomarkers of chronic kidney damage and renal functional decline in childhood-onset systemic lupus erythematosus
To delineate urine biomarkers that reflect kidney structural damage and predict renal functional decline in pediatric lupus nephritis (LN).
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Open AccessPilot study comparing the childhood arthritis and rheumatology research alliance consensus treatment plans for induction therapy of juvenile proliferative lupus nephritis
To reduce treatment variability and facilitate comparative effectiveness studies, the Childhood Arthritis and Rheumatology Research Alliance (CARRA) published consensus treatment plans (CTPs) including one for...
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Open AccessDevelo** consensus treatment plans for proliferative lupus nephritis in childhood-onset systemic lupus erythematous
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Article
Open AccessAsymptomatic intracardiac mass in a 14-year-old girl with granulomatosis with polyangiitis: Case report
Granulomatosis with polyangiitis (GPA; Wegener’s granulomatosis) is a systemic necrotizing vasculitis of unknown etiology that commonly involves the upper airways, lungs, and kidneys. Cardiac involvement with ...
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Initial Validation of a Novel Protein Biomarker Panel for Active Pediatric Lupus Nephritis
Lupus nephritis (LN) is among the main determinants of poor prognosis in systemic lupus erythematosus (SLE). The objective of this study was to 1) isolate and identify proteins contained in the LN urinary prot...
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Neutrophil gelatinase-associated lipocalin as a biomarker of disease activity in pediatric lupus nephritis
We hypothesized that neutrophil gelatinase-associated lipocalin (NGAL) is an early predictive biomarker of disease activity in lupus nephritis. NGAL in serial plasma (PNGAL) and urine (UNGAL) samples was measu...
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Article
Systemic lupus erythematosus
Systemic Lupus Erythematosus (SLE) of childhood is a complex and challenging disease which can occur at any age. Identification of disease early in it's course and aggressive, appropriate management leads to i...
