15 Result(s)

Article

Juvenile dermatomyositis: association between nail fold capillary end row loop– area under the curve– and disease damage indicators

Juvenile Dermatomyositis (JDM) is a rare autoimmune disease characterized by skin and muscle inflammation. The loss of nail fold capillary end row loops (ERL) is evidence of small vessel involvement in JDM. Th...

Amer Khojah, Gabrielle Morgan, Marisa S. Klein-Gitelman… in Pediatric Rheumatology (2023)

Article

Nailfold capillary density in 140 untreated children with juvenile dermatomyositis: an indicator of disease activity

We lack a reliable indicator of disease activity in Juvenile Dermatomyositis (JDM), a rare disease. The goal of this study is to identify the association of nailfold capillary End Row Loop (ERL) loss with dise...

Lauren M. Pachman, Gabrielle Morgan, Marisa S. Klein-Gitelman… in Pediatric Rheumatology (2023)

Article

Rituximab-associated Hypogammaglobulinemia in pediatric patients with autoimmune diseases

Despite the increased use of rituximab in treating pediatric patients with autoimmune diseases in the last decade, there are limited data on rituximab safety in those subjects who have a develo** immune syst...

Amer M. Khojah, Michael L. Miller, Marisa S. Klein-Gitelman… in Pediatric Rheumatology (2019)

Article

Pilot study comparing the childhood arthritis and rheumatology research alliance consensus treatment plans for induction therapy of juvenile proliferative lupus nephritis

To reduce treatment variability and facilitate comparative effectiveness studies, the Childhood Arthritis and Rheumatology Research Alliance (CARRA) published consensus treatment plans (CTPs) including one for...

Jennifer C Cooper, Kelly Rouster-Stevens, Tracey B Wright… in Pediatric Rheumatology (2018)

Article

Urine S100 proteins as potential biomarkers of lupus nephritis activity

Improved, noninvasive biomarkers are needed to accurately detect lupus nephritis (LN) activity. The purpose of this study was to evaluate five S100 proteins (S100A4, S100A6, S100A8/9, and S100A12) in both seru...

Jessica L. Turnier, Ndate Fall, Sherry Thornton… in Arthritis Research & Therapy (2017)

Article

An Update on Treatment and Management of Pediatric Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disorder in which 20 % of patients are diagnosed in childhood. Childhood-onset SLE is associated with higher morbidity and mortality than ...

Amit Thakral, Marisa S. Klein-Gitelman in Rheumatology and Therapy (2016)

Article

Functional neuronal network activity differs with cognitive dysfunction in childhood-onset systemic lupus erythematosus

Neuropsychiatric manifestations are common in childhood-onset systemic lupus erythematosus (cSLE) and often include neurocognitive dysfunction (NCD). Functional magnetic resonance imaging (fMRI) can measure br...

Mark W DiFrancesco, Darren R Gitelman… in Arthritis Research & Therapy (2013)

Article

Develo** consensus treatment plans for proliferative lupus nephritis in childhood-onset systemic lupus erythematous

Rina Mina, Hermine Brunner, Barbara Anne Eberhard… in Pediatric Rheumatology (2012)

Article

Asymptomatic intracardiac mass in a 14-year-old girl with granulomatosis with polyangiitis: Case report

Granulomatosis with polyangiitis (GPA; Wegener’s granulomatosis) is a systemic necrotizing vasculitis of unknown etiology that commonly involves the upper airways, lungs, and kidneys. Cardiac involvement with ...

Julia G Harris, David M Salvay, Marisa S Klein-Gitelman in Pediatric Rheumatology (2012)

Article

Initial Validation of a Novel Protein Biomarker Panel for Active Pediatric Lupus Nephritis

Lupus nephritis (LN) is among the main determinants of poor prognosis in systemic lupus erythematosus (SLE). The objective of this study was to 1) isolate and identify proteins contained in the LN urinary prot...

Michiko Suzuki, Kristina Wiers, Elizabeth B Brooks, Kenneth D Greis… in Pediatric Research (2009)