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Article

Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer

Broad-spectrum RAS inhibition has the potential to benefit roughly a quarter of human patients with cancer whose tumours are driven by RAS mutations^1,2. RMC-7977 is a highly selective inhibitor of the active GTP-...

Urszula N. Wasko, **g**g Jiang, Tanner C. Dalton, Alvaro Curiel-Garcia… in Nature (2024)