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  1. Article

    Open Access

    Genomes reveal marked differences in the adaptive evolution between orangutan species

    Integrating demography and adaptive evolution is pivotal to understanding the evolutionary history and conservation of great apes. However, little is known about the adaptive evolution of our closest relatives...

    Maja P. Mattle-Greminger, Tugce Bilgin Sonay, Alexander Nater, Marc Pybus in Genome Biology (2018)

  2. No Access

    Article

    Genomic analysis of Andamanese provides insights into ancient human migration into Asia and adaptation

    Jaume Bertranpetit, Partha Majumder and colleagues analyze whole-genome sequences from Andamanese individuals and compare them to sequences from mainland Indian and other geographically diverse populations. Th...

    Mayukh Mondal, Ferran Casals, Tina Xu, Giovanni M Dall'Olio, Marc Pybus in Nature Genetics (2016)

  3. Article

    Open Access

    Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences

    Population differentiation has proved to be effective for identifying loci under geographically localized positive selection, and has the potential to identify loci subject to balancing selection. We have prev...

    Vincenza Colonna, Qasim Ayub, Yuan Chen, Luca Pagani, Pierre Luisi in Genome Biology (2014)

  4. Article

    Open Access

    Sum of parts is greater than the whole: inference of common genetic history of populations

    Reconstructability of population history, from genetic information of extant individuals, is studied under a simulation setting. We do not address the issue of accuracy of the reconstruction algorithms: we ass...

    Filippo Utro, Marc Pybus, Laxmi Parida in BMC Genomics (2013)