10 Result(s)

Article

Circulating 25-hydroxyvitamin D and survival outcomes of colorectal cancer: evidence from population-based prospective cohorts and Mendelian randomisation

To investigate the association between circulating 25-hydroxyvitamin D (25-OHD) and colorectal cancer (CRC) survival outcomes.

**aomeng Zhang, Yazhou He, Xue Li, Rasha Shraim, Wei Xu… in British Journal of Cancer (2024)

Article

Dissecting the pathogenic effects of smoking and its hallmarks in blood DNA methylation on colorectal cancer risk

Tobacco smoking is suggested as a risk factor for colorectal cancer (CRC), but the complex relationship and the potential pathway are not fully understood.

Xuan Zhou, Qian **ao, Fangyuan Jiang, **g Sun, Lijuan Wang… in British Journal of Cancer (2023)

Article

Genetic risk scores may compound rather than solve the issue of prostate cancer overdiagnosis

Rachel H. Horton, Malcolm G. Dunlop, Richard S. Houlston… in British Journal of Cancer (2023)

Article

Phenome-wide association study (PheWAS) of colorectal cancer risk SNP effects on health outcomes in UK Biobank

Associations between colorectal cancer (CRC) and other health outcomes have been reported, but these may be subject to biases, or due to limitations of observational studies.

**aomeng Zhang, Xue Li, Yazhou He, Philip J. Law… in British Journal of Cancer (2022)

Article

Genetically predicted physical activity levels are associated with lower colorectal cancer risk: a Mendelian randomisation study

We conducted a Mendelian randomisation (MR) study to investigate whether physical activity (PA) causes a reduction of colorectal cancer risk and to understand the contributions of effects mediated through chan...

**aomeng Zhang, Evropi Theodoratou, Xue Li… in British Journal of Cancer (2021)

Article

The effect of vitamin D supplementation on survival in patients with colorectal cancer: systematic review and meta-analysis of randomised controlled trials

Low circulating vitamin D levels are associated with poor colorectal cancer (CRC) survival. We assess whether vitamin D supplementation improves CRC survival outcomes.

Peter G. Vaughan-Shaw, Louis F. Buijs, James P. Blackmur… in British Journal of Cancer (2020)

Article

Genome-wide scan of the effect of common nsSNPs on colorectal cancer survival outcome

We conducted a genome-wide scan to identify non-synonymous SNPs (nsSNPs) that might influence survival after a diagnosis of colorectal cancer (CRC).

Evropi Theodoratou, Susan M Farrington, Maria Timofeeva… in British Journal of Cancer (2018)

Article

Erratum: Evidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia

Stephanie A Schubert, Dina Ruano, Fadwa A Elsayed, Arnoud Boot… in British Journal of Cancer (2018)

Article

Evidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia

A substantial fraction of familial colorectal cancer (CRC) and polyposis heritability remains unexplained. This study aimed to identify predisposing loci in patients with these disorders.

Stephanie A Schubert, Dina Ruano, Fadwa A Elsayed, Arnoud Boot… in British Journal of Cancer (2017)

Article

Mendelian randomisation analysis strongly implicates adiposity with risk of develo** colorectal cancer

Observational studies have associated adiposity with an increased risk of colorectal cancer (CRC). However, such studies do not establish a causal relationship. To minimise bias from confounding we performed a...

David Jarvis, Jonathan S Mitchell, Philip J Law, Kimmo Palin… in British Journal of Cancer (2016)