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Immunological tumor destruction in a murine melanoma model by targeted LTα independent of secondary lymphoid tissue

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  1. Article

    Open Access

    High frequencies of circulating memory T cells specific for calreticulin exon 9 mutations in healthy individuals

    Mutations in exon 9 of the calreticulin gene (CALR) frequently occur in patients with chronic myeloproliferative neoplasms (MPN). Patients exhibit spontaneous cellular immune responses to epitopes derived from th...

    Morten O. Holmström, Shamaila M. Ahmad, Uffe Klausen… in Blood Cancer Journal (2019)

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  2. Article

    Open Access

    Survivin-specific T-cell reactivity correlates with tumor response and patient survival: a phase-II peptide vaccination trial in metastatic melanoma

    Therapeutic vaccination directed to induce an anti-tumoral T-cell response is a field of extensive investigation in the treatment of melanoma. However, many vaccination trials in melanoma failed to demonstrate...

    Jürgen C. Becker, Mads H. Andersen… in Cancer Immunology, Immunotherapy (2012)

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