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  1. Article

    Open Access

    Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific association for the study of the liver (APASL): an update

    The first consensus report of the working party of the Asian Pacific Association for the Study of the Liver (APASL) set up in 2004 on acute-on-chronic liver failure (ACLF) was published in 2009. With internati...

    Shiv Kumar Sarin, Ashok Choudhury, Manoj K. Sharma… in Hepatology International (2019)

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  2. No Access

    Article

    Hepatitis C elimination: a Public Health Perspective

    Hepatitis C virus (HCV) infection is a principal cause of morbidity, mortality, and economic burden, and the global elimination of HCV is now considered a public health objective. Globally, an estimated 71 mil...

    Radha K. Dhiman, Gagandeep S. Grover… in Current Treatment Options in Gastroenterol… (2019)

  3. Article

    Open Access

    Correction to: Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific association for the study of the liver (APASL): an update

    The article Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific association for the study of the liver (APASL): an update, written by [Shiv Sarin], was originally published electroni...

    Shiv Kumar Sarin, Ashok Choudhury, Manoj K. Sharma… in Hepatology International (2019)

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  4. No Access

    Chapter

    Acute on Chronic Liver Failure

    A 32-year-old male, an alcohol consumer (150 gm/day × 5 years), and recent history of binge alcohol intake now presents with progressive jaundice for one month followed by abdominal distension for 15 days. The...

    Madhumita Premkumar, Akash Roy, Virendra Singh in Clinical Rounds in Hepatology (2022)

  5. No Access

    Chapter

    Gene Therapy in Liver Disease: Challenges and Outcomes

    Liver-directed gene therapy (LDGT) has been proposed as a means of treating many single-gene inherited disorders. LDGT has been used to create genetic pharmacological products that can be used for treatment of...

    Madhumita Premkumar, Virendra Singh in Biomedical Translational Research (2022)

  6. Article

    Open Access

    Safety and efficacy of terlipressin in acute-on-chronic liver failure with hepatorenal syndrome-acute kidney injury (HRS-AKI): a prospective cohort study

    Terlipressin with albumin, the recommended treatment for hepatorenal syndrome-acute kidney injury (HRS-AKI), is associated with adverse events. Furthermore, the course of AKI in patients with acute-on-chronic ...

    Anand V. Kulkarni, Sowmya Tirumalige Ravikumar, Harshvardhan Tevethia… in Scientific Reports (2022)

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  7. No Access

    Article

    Fecal microbiota transplantation in alcohol-associated acute-on-chronic liver failure: an open-label clinical trial

    Severe alcoholic hepatitis (SAH) presenting as acute-on-chronic liver failure (ACLF) carries a high short-term mortality. Alteration of gut microbiota is a crucial component implicated in its pathogenesis, who...

    Anima Sharma, Akash Roy, Madhumita Premkumar, Nipun Verma… in Hepatology International (2022)

  8. No Access

    Article

    Neurological monitoring and sedation protocols in the Liver Intensive Care Unit

    Patients with liver disease often have alteration of neurological status which requires admission to an intensive care unit. Patients with acute liver failure (ALF), acute-on-chronic liver failure (ACLF) and r...

    Rohit Mehtani, Shankey Garg, Kamal Kajal, Shiv Lal Soni… in Metabolic Brain Disease (2022)

  9. No Access

    Article

    Nutrition in Critical Care Hepatology

    Patients with cirrhosis necessitating admission to the intensive care unit are often malnourished and have a high short-term mortality. This review describes the role of nutritional therapy in improving outcom...

    Rohit Mehtani, Madhumita Premkumar, Anand V. Kulkarni in Current Hepatology Reports (2022)

  10. Article

    Association of Heparin-Like Effect, Factor VII/XIII Deficiency and Fibrinolysis with Rebleeding Risk in Cirrhosis with Acute Variceal Bleeding

    Hyperfibrinolysis and coagulation dysfunction may occur in cirrhotic patients with acute variceal bleed (AVB) despite successful endotherapy.

    Madhumita Premkumar, Rohit Mehtani, Anand V. Kulkarni… in Digestive Diseases and Sciences (2023)

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  11. Article

    Antibody Response and Safety of ChAdOx1-nCOV (Covishield) in Patients with Cirrhosis: A Cross-Sectional, Observational Study

    Patients with cirrhosis have a higher risk of severe COVID-19 and mortality and are high-priority patients for vaccination. However, cirrhotics were excluded from the phase 2/3 vaccine trials. Hence, we aimed ...

    Amandeep Singh, Arka De, Mini P. Singh, Sahaj Rathi… in Digestive Diseases and Sciences (2023)

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  12. No Access

    Article

    Simple bedside tests of muscle strength and function correlate with computed tomography-skeletal muscle index for assessment of sarcopenia in cirrhosis

    Sarcopenia assessment can be done by skeletal muscle index (SMI) or bedside tests such as handgrip strength (HGS) and gait speed (GS).

    Surender Singh, Sunil Taneja, Akash Roy, Sahaj Rathi… in Indian Journal of Gastroenterology (2023)

  13. No Access

    Article

    Prevalence, Risk Factors, and Impact of Bacterial or Fungal Infections in Acute Liver Failure Patients from India

    We evaluated the prevalence, risk factors, and impact of bacterial/fungal infections in acute liver failure (ALF) patients.

    Parminder Kaur, Nipun Verma, Arun Valsan, Pratibha Garg… in Digestive Diseases and Sciences (2023)

  14. No Access

    Article

    Perceptions regarding the impact of gender on training and career advancement among gastroenterologists in India and other South Asian countries

    There are limited studies on the impact of gender on training and career advancement in gastroenterology.

    Shubhra Mishra, Anuraag Jena, Loren Galler Rabinowitz… in Indian Journal of Gastroenterology (2024)

  15. No Access

    Article

    Critical care management of acute liver failure

    The management of acute liver failure (ALF) in modern hepatology intensive care units (ICU) has improved patient outcomes. Critical care management of hepatic encephalopathy, cerebral edema, fluid and electrol...

    Surender Singh Sehrawat, Madhumita Premkumar in Indian Journal of Gastroenterology (2024)

  16. No Access

    Article

    Partial Reversal of Shunt Myelopathy and Hepatic Parkinsonism Using Balloon-Occluded Retrograde Transvenous Obliteration

    Amar Mukund, Madhumita Premkumar… in CardioVascular and Interventional Radiology (2024)

  17. No Access

    Article

    Point-of-care ultrasound permits early initiation of terlipressin in suspected hepatorenal syndrome-acute kidney injury: A single arm proof-of-concept report

    Akash Roy, Madhumita Premkumar, Indrajeet Tiwary… in Indian Journal of Gastroenterology (2024)