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  1. Article

    Open Access

    Irinotecan and its metabolite SN38 inhibits procollagen I production of dermal fibroblasts from Systemic Sclerosis patients

    Systemic sclerosis (SSc) is a rare autoimmune connective tissue disease characterized by a microangiopathy and fibrosis of the skin and internal organs. No treatment has been proved to be efficient in case of ...

    J. Lapoirie, L. Tran, L. Piazza, C. Contin-Bordes, M. E. Truchetet in Scientific Reports (2021)