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Article
Biomarkers of cardiovascular risk in sleep-deprived people
The global increase in both coronary heart disease (CHD) and cardiovascular disease (CVD) and the associated increase in undetected subclinical cardiovascular pathology highlight the continuing need for improv...
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Article
Focal amplification and oncogene dependency of GAB2 in breast cancer
DNA amplifications in breast cancer are frequent on chromosome 11q, in which multiple driver oncogenes likely reside in addition to cyclin D1 (CCND1). One such candidate, the scaffolding adapter protein, GRB2-ass...
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Article
New cutpoints to identify increased HER2 copy number: analysis of a large, population-based cohort with long-term follow-up
Background HER2 gene amplification and/or protein overexpression in breast cancer is associated with a poor prognosis and predicts response to anti-HER2 therapy. We examine the natural hi...
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Article
Cellular adhesion molecules and their relationship with measures of obesity and metabolic syndrome in a multiethnic population
The relationships between adhesion molecules and measures of obesity and metabolic syndrome in different ethnic populations are unclear.
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Selected U.S. Government Sponsored Women’s Health Menopause Initiatives: Session Summary
Issues related to women’s health, and particularly to menopause, have been major priorities over the past decade for agencies of the U.S. Department of Health and Human Services (DHHS). In order to prevent mor...