1,728 Result(s)
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Open AccessEfficacy and safety of oral semaglutide vs sitagliptin in a predominantly Chinese population with type 2 diabetes uncontrolled with metformin: PIONEER 12, a double-blind, Phase IIIa, randomised trial
The aim of this study was to assess the efficacy and safety of oral semaglutide vs sitagliptin in a predominantly Chinese population with type 2 diabetes inadequately controlled with metformin treatment.
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Open Access“Textbook outcome(s)” in colorectal surgery: a systematic review and meta-analysis
Textbook outcome (TO) is a composite measure used in surgery to evaluate post operative outcomes. No review has synthesised the evidence in relation to TO regarding the elements surgeons are utilising to infor...
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Open AccessSingle-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 h
Disruption of pancreatic islet function and glucose homeostasis can lead to the development of sustained hyperglycaemia, beta cell glucotoxicity and subsequently type 2 diabetes. In this study, we explored the...
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Open AccessCorrection: Impact of non-pharmaceutical interventions during COVID-19 on future influenza trends in Mainland China
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Quantitative metrics of the LV trabeculated layer by cardiac CT and cardiac MRI in patients with suspected noncompaction cardiomyopathy
To compare cardiac computed tomography (CCT) and cardiac magnetic resonance (CMR) for the quantitative assessment of the left ventricular (LV) trabeculated layer in patients with suspected noncompaction cardio...
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Open AccessGadolinium-enhanced intracranial aneurysm wall imaging and risk of aneurysm growth and rupture: a multicentre longitudinal cohort study
In patients with an unruptured intracranial aneurysm, gadolinium enhancement of the aneurysm wall is associated with growth and rupture. However, most previous studies did not have a longitudinal design and di...
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Open AccessAssociation between COVID-19 convalescent plasma antibody levels and COVID-19 outcomes stratified by clinical status at presentation
There is a need to understand the relationship between COVID-19 Convalescent Plasma (CCP) anti-SARS-CoV-2 IgG levels and clinical outcomes to optimize CCP use. This study aims to evaluate the relationship betw...
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Open AccessAuswirkungen der Pflegevisite auf die Prozessverantwortliche Pflege
An einem Universitätsklinikum wurde die Pflegevisite (PV) auf einer Intensivstation (ITS) nach einer Pilotphase im Jahr 2017 implementiert. Bisher fehlt es an publizierten Erkenntnissen zur Auswirkung der PV a...
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Open AccessZertifizierungsrichtlinien der Österreichischen Gesellschaft für Schlafmedizin und Schlafforschung (ÖGSM) für schlafmedizinische Einrichtungen in Österreich
Die Zertifizierung von Schlaflaboren ist eine notwendige Voraussetzung zur Qualitätssicherung für den Betrieb eines Schlaflabors und wird von der Österreichischen Gesellschaft für Schlafmedizin und Schlafforsc...
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Human-in-the-loop avatar chatbot shows promise in supporting hematopoietic stem cell transplantation patients
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Open AccesseNAMPT is a novel therapeutic target for mitigation of coronary microvascular disease in type 2 diabetes
Individuals with diabetes are at high risk of cardiovascular complications, which significantly increase morbidity/mortality. Coronary microvascular disease (CMD) is recognised as a critical contributor to the...
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Open AccessSmart mandibular advancement devices for obstructive sleep apnea: a systematic literature review
The goal of this review is to provide sleep physicians, dentists, and researchers with an evidence-based overview of the literature on smart mandibular advancement devices (MADs) for the treatment of obstructi...
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Open AccessThe Multidimensional Prognostic Index predicts incident delirium among hospitalized older patients with COVID-19: a multicenter prospective European study
Testing the role of the Multidimensional Prognostic Index (MPI), based on the Comprehensive Geriatric Assessment (CGA), in predicting the risk of incident delirium in hospitalized older patients with COVID-19.
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Open AccessAnalysis of Top 100 Articles Cited in Top Pain Journals: A Comprehensive Two Decade Bibliometric Analysis
A bibliometric analysis was performed to analyze and compare the top 100 articles from the most well-known five pain journals: Pain, Pain Physician, Pain Medicine, Regional Anesthesia & Pain Medicine, and Journal...
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Effectiveness of a Population Health Intervention on Disparities in Hypertension Control: A Stepped Wedge Cluster Randomized Clinical Trial
Disparities in hypertension control across race, ethnicity, and language have been a long-standing problem in the United States.
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Kenntnisse und tatsächliche Umsetzung der Empfehlungen zur Prävention des plötzlichen Säuglingstods innerhalb des ersten Lebensjahres – eine Analyse longitudinaler Daten der KUNO Kids Gesundheitsstudie
Der plötzliche Säuglingstod (sudden infant death syndrome [SIDS]) ist immer noch eine der wichtigsten Todesursachen im Säuglingsalter.
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DACH1 attenuated PA-induced renal tubular injury through TLR4/MyD88/NF-κB and TGF-β/Smad signalling pathway
Palmitic acid (PA), the major saturated fatty acid in the blood, often induces the initiation and progression of diabetic kidney disease (DKD). However, the underlying mechanism remains unclear. DACH1 is an im...
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Gangstörungen - was der Hausarzt wissen sollte
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Hormonersatztherapie in den Wechseljahren
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Open AccessFrailty as an Effect Modifier in Randomized Controlled Trials: A Systematic Review
The effect of clinical interventions may vary by patients’ frailty status. Understanding treatment effect heterogeneity by frailty could lead to frailty-guided treatment strategies and reduce overtreatment and...