32 Result(s)

Article

Counterflow centrifugal elutriation as a method of T cell depletion may cause loss of immature CD34⁺ cells

Counterflow centrifugal elutriation (CCE) is capable of separating cells on the basis of size. CCE has been used successfully to deplete allogeneic bone marrow (BM) grafts of T lymphocytes to decrease the risk...

Q Chang, K Harvey, L Akard, J Thompson, M Dugan, D English… in Bone Marrow Transplantation (1997)

Article

T cell-depleted granulocyte colony-stimulating factor (G-CSF) modified allogeneic bone marrow transplantation for hematological malignancy improves graft CD34⁺ cell content but is associated with delayed pancytopenia

To increase the stem cell content of T cell-depleted bone marrow transplants (BMT), we treated 12 patients with hematological malignancies with BMT from HLA-identical sibling donors given G-CSF 10 μg/kg/day fo...

DA Mavroudis, EJ Read, J Molldrem, A Raptis, M Plante… in Bone Marrow Transplantation (1998)

Article

Niemann–Pick disease type C (a cellular cholesterol lipidosis) treated by bone marrow transplantation

Bone marrow transplantation (BMT) has been used for a wide variety of lysosomal storage diseases with encouraging results. We report a 3-year 5-month-old girl with Niemann–Pick type C disease (NPC) who receive...

Y-S Hsu, W-L Hwu, S-F Huang, M-Y Lu, R-L Chen, D-T Lin… in Bone Marrow Transplantation (1999)

Article

Ex vivo expansion of enriched CD34⁺ cells from neonatal blood in the presence of thrombopoietin, a comparison with cord blood and bone marrow

Neonatal blood (NB) contains substantial numbers of stem and progenitor cells which decline rapidly after birth. Using a combination of cord blood (CB) and NB, we performed a successful, sibling transplant for...

J Liu, K Li, PMP Yuen, TF Fok, FW Yau, M Yang, CK Li in Bone Marrow Transplantation (1999)

Article

Symptom burden in patients undergoing autologous stem-cell transplantation

Patients who undergo autologous peripheral blood stem cell (PBSC) transplantation experience multiple symptoms that adversely affect quality of life. We assessed symptoms during the acute phase of autologous P...

K O Anderson, S A Giralt, T R Mendoza, J O Brown… in Bone Marrow Transplantation (2007)

Article

Current status of hematopoietic stem cell transplantation in Taiwan

In Taiwan, hematopoietic SCT (HSCT) has been used to treat patients with hematological diseases since 1983. Since then, more than 2200 patients have undergone HSCT in 15 large hospitals. The disease entities i...

P-M Chen, L-T Hsiao, M-Huang Chen, P M-S Chang, C-Y Liu… in Bone Marrow Transplantation (2008)

Article

Therapeutic potential of non-adherent BM-derived mesenchymal stem cells in tissue regeneration

We demonstrated that non-adherent BM cells (NA-BMCs) can be expanded in suspension and give rise to multiple mesenchymal phenotypes including fibroblastic, osteoblastic, chondrocytic and adipocytic as well as ...

Z L Zhang, J Tong, R N Lu, A M Scutt, D Goltzman, D S Miao in Bone Marrow Transplantation (2009)

Article

Are there roles for observational database studies and structured quantification of expert opinion to answer therapy controversies in transplants?

Approaches to determine whether one transplant-related therapy is better than another include: (1) using experimental data, such as those from randomized controlled trials (RCTs); (2) using observational data,...

R P Gale, M Eapen, B Logan, M-J Zhang, H M Lazarus in Bone Marrow Transplantation (2009)

Article

Effects of Azithromycin in bronchiolitis obliterans syndrome after hematopoietic SCT—a randomized double-blinded placebo-controlled study

Bronchiolitis obliterans syndrome (BOS) is an important complication after hematopoietic SCT (HSCT). Recent observations suggested that azithromycin might improve lung function in BOS after HSCT. We conducted ...

D C L Lam, B Lam, M K Y Wong, C Lu, W Y Au, E W C Tse… in Bone Marrow Transplantation (2011)

Article

The anti-tumour activity of allogeneic cytokine-induced killer cells in patients who relapse after allogeneic transplant for haematological malignancies

We performed a Phase I/II clinical trial to study the feasibility, toxicity and efficacy of allogeneic cytokine-induced killer (CIK) cell expansion, and treatment for patients with haematological malignancies ...

Y-C Linn, M Niam, S Chu, A Choong, H-X Yong, K-K Heng… in Bone Marrow Transplantation (2012)

Article

Bronchiolitis obliterans after allo-SCT: clinical criteria and treatment options

Bronchiolitis obliterans (BO) following allogeneic haematopoietic SCT (HSCT) is a serious complication affecting 1.7–26% of the patients, with a reported mortality rate of 21–100%. It is considered a manifesta...

H H Uhlving, F Buchvald, C J Heilmann, K G Nielsen… in Bone Marrow Transplantation (2012)

Article

Second malignancies after autologous hematopoietic cell transplantation in children

Childhood autologous hematopoietic cell transplant (auto-HCT) survivors can be at risk for secondary malignant neoplasms (SMNs). We assembled a cohort of 1487 pediatric auto-HCT recipients to investigate the i...

K E Danner-Koptik, N S Majhail, R Brazauskas, Z Wang… in Bone Marrow Transplantation (2013)

Article

Second cancer risk in adults receiving autologous haematopoietic SCT for cancer: a population-based cohort study

Population-based evidence on second cancer risk following autologous haematopoietic SCT (HCT) is lacking. We quantified second cancer risk for a national, population-based cohort of adult Australians receiving...

I A Bilmon, L J Ashton, R E Le Marsney, A J Dodds… in Bone Marrow Transplantation (2014)

Article

Baseline body mass index among children and adults undergoing allogeneic hematopoietic cell transplantation: clinical characteristics and outcomes

Obesity is an important public health problem that may influence the outcomes of hematopoietic cell transplantation (HCT). We studied 898 children and adults receiving first-time allogeneic hematopoietic SCTs ...

M Gleimer, Y Li, L Chang, S Paczesny, D A Hanauer, D G Frame… in Bone Marrow Transplantation (2015)

Article

A review of the genetic and long-term effects of G-CSF injections in healthy donors: a reassuring lack of evidence for the development of haematological malignancies

In 2007 the WMDA responded to the publication of two manuscripts suggesting a causal link between G-CSF and myeloid malignancies in healthy donors by convening an international symposium to examine this issue....

B E Shaw, D L Confer, W Hwang, M A Pulsipher in Bone Marrow Transplantation (2015)

Article

Human herpesvirus 6B reactivation and delirium are frequent and associated events after cord blood transplantation

Human herpesvirus 6B (HHV-6B) frequently reactivates after cord blood transplantation (CBT). We previously reported an association between HHV-6B reactivation and delirium after hematopoietic cell transplantat...

J A Hill, M Boeckh, W M Leisenring, H **e, A L Adler… in Bone Marrow Transplantation (2015)

Article

Analytic morphomics: a novel CT imaging approach to quantify adipose tissue and muscle composition in allogeneic hematopoietic cell transplantation

K Chughtai, Y Song, P Zhang, B Derstine, E Gatza, J Friedman… in Bone Marrow Transplantation (2016)

Article

Inadvertent completely HLA-mismatched allogeneic unrelated bone marrow transplant: lessons learned

B S Sorensen, J Szer, B Shaw, M Korhonen, T Mengling… in Bone Marrow Transplantation (2016)

Article

The experience of survival following allogeneic haematopoietic stem cell transplantation in New South Wales, Australia

Allogeneic haematopoietic stem cell transplantation (allo-HSCT) entails long-term morbidities that impair survivors’ quality of life through broad physical and psychosocial sequelae. Current data and survival ...

G Gifford, N Gilroy, G Dyer, L Brice, M Kabir, M Greenwood… in Bone Marrow Transplantation (2016)

Article

Advance care planning and end-of-life care for patients with hematologic malignancies who die after hematopoietic cell transplant

E E Eckhert, K L Schoenbeck, D Galligan, L M McNey, J Hwang… in Bone Marrow Transplantation (2017)